Raloxifene
84449-90-1 Basic informationMore
- Product Name:Raloxifene
- Synonyms: [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-y1][4-[2-(1-piperidinyl)ethoxy]phenyl]methamone [4-[2-(1-Piperidinyl) Ethoxy] Phenyl]methanone.HCL RALOXAFINE [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone [6-hydroxy-2-(4-hydroxyphenyl)benzothiophen-3-yl]-[4-[2-(1-piperidyl)ethoxy]phenyl]methanone hydrochloride Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]- [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl] ketone [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone
- CAS:84449-90-1
- MF:C28H27NO4S
- MW:473.58
- EINECS:686-786-1
- Mol File:84449-90-1.mol
USE
Raloxifene, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone (Evista), is a benzothiophene derivativethat differs slightly from the triphenylethyleneSERMs. A key structural difference is the carbonyl “hinge”that connects the modified phenolic side chain to the benzothiophenering system. This hinge is the key structural elementthat leads to the differing actions at the ERs.Raloxifene, unlike tamoxifen and toremifene, has antagonistproperties on the endometrium and breast tissue and agonistproperties on bone and the cardiovascular system. The lackof agonist action on endometrial tissue has been suggestedas a reason for the lack of endometrial cancer associatedwith raloxifene use. Raloxifene is approved for the preventionand treatment of osteoporosis in postmenopausalwomen. It has also been investigated for preventing breastcancer in comparison with tamoxifen. Recent studies indicatesthat it has similar effectiveness to tamoxifen, but has apreferable side effect profile.
Lastest Price from Raloxifene manufacturers
- Raloxifene
- US $10.00-0.00/g
- CAS:84449-90-1
- Min. Order: 1g
- Purity: 98%+
- Supply Ability: 100kgs
- 2024-11-01
- Raloxifene
- US $1330.00 /kg
- CAS:84449-90-1
- Min. Order: 0.1kg
- Purity: 99% min
- Supply Ability: 20 tons
- 2024-09-25
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:Raloxifene hydrochloride;[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-Methanonehydrochloride
CAS:84449-90-1
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
- Related Information:Catalog(15839)
- Company Name:Daicel Chiral Technologies (China)CO.,LTD
- Tel:021-50460086-9 15921403865
- Products Intro:Product Name:4-(6-hydroxybenzo[b]thiophen-2-yl)benzene-1,3-diol
Purity:95% HPLC Package:10MG ;25MG;50MG;100MG Remarks:DCTI-C-270 - CB Index:65
- Related Information:Catalog(7195)
- Company Name:China Langchem Inc.
- Tel:021-58956006 15800617331
- Products Intro:Product Name:Raloxifene
CAS:84449-90-1
Purity:98% Package:1kg;5kg;100kg Remarks:1g/400 More... - CB Index:57
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- Company Name:Shanghai Topbiochem Technology Co., Ltd
- Tel:021-58170097
- Products Intro:Product Name:Raloxifene
CAS:84449-90-1
Purity:98% - CB Index:58
- Related Information:Catalog(9458)
- Company Name:Chengdu Aslee Biopharmaceuticals, Inc
- Tel:028-85305008 02885305008
- Products Intro:Product Name:Raloxifene
CAS:84449-90-1
More... - CB Index:50
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