Crizotinib
877399-52-5 Basic informationMore
- Product Name:Crizotinib
- Synonyms: (R)-3-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H- pyrazol-4-yl)pyridin-2-ylaMine [3-[[(R)-1-(2,6-Dichloro-3- fluorophenyl)ethyl]oxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-yl]aMine 2-PyridinaMine, 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]- Crozotinib Crizotinib,PF-02341066 Crizotinib (PF2341066) PF-02341066 Crizotinib 3-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
- CAS:877399-52-5
- MF:C21H22Cl2FN5O
- MW:450.34
- EINECS:638-814-9
- Mol File:877399-52-5.mol
USE
Crizotinib (Xalkori(R), Pfizer), approved in 2011, was the first approved inhibitor targeting anaplastic lymphoma kinase (ALK). ROS protooncogene 1-encoded kinase (ROS1) of the tyrosine kinase insulin receptor class and MET proto-oncogene-encoded kinase of the hepatocyte growth factor receptor (HGFR) class are other kinases targeted by crizotinib.When approved in 2011, crizotinib was the first drug specifically targeting NSCLC patients. However, resistance to crizotinib was usually observed in approximately 8 months after initial application and more than half of crizotinib-treated patients experienced gastrointestinal side effects. In 2016,crizotinib was additionally approved for ROS1-positive NSCLC by FDA.
Lastest Price from Crizotinib manufacturers
- Crizotinib
- US $0.00-0.00/kg
- CAS:877399-52-5
- Min. Order: 1kg
- Purity: 99%,single impurity<0.1
- Supply Ability: 1 ton
- 2024-11-21
- Crizotinib
- US $1.00-0.50/kg
- CAS:877399-52-5
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 200kg
- 2024-11-21
Browse by Nationality 877399-52-5 Suppliers >Global suppliers
Beijing (18) Shanghai (123) Chongqing (3) Sichuan (5) Guangdong (35) Zhejiang (33) Fujian (3) Hunan (6) Hubei (97) Shandong (25) Henan (15) Hebei (11) Liaoning (2) Anhui (16) Jiangsu (66) Jiangxi (4) Shaanxi (7) Hong Kong (5) Member (465) All (474)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:Hubei Dibai Chemical Co., Ltd.
- Tel:027-87058617 15872383390
- Products Intro:Product Name:Crizotinib
CAS:877399-52-5
Purity:99.5% HPLC Package:1000KG More... - CB Index:58
- Related Information:Catalog(885)
- Company Name:Hangzhou Chemtrue Bio-Tech Co.,Ltd.
- Tel:0571-86828652 18857119830
- Products Intro:Product Name:Crizotinib
CAS:877399-52-5
Purity:99% HPLC Package:100g;1KG;5KG;25KG More... - CB Index:58
- Related Information:Catalog(322)
- Company Name:Tai Zhou World Pharm & Chem Co., Ltd
- Tel:0576-85301198 13736201658
- Products Intro:Product Name:(R)-3-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-(1-piper
idin-4-yl-1H- pyrazol-4-yl)pyridin-2-ylaMine
CAS:877399-52-5
Purity:99% HPLC Package:500KG;100KG;25KG;5KG;1KG - CB Index:58
- Related Information:Catalog(104)
- Company Name:Jinan XinKe Pharmaceutical Technology Co., Ltd.
- Tel:0531-88259693 17854196142
- Products Intro:Product Name:Crizotinib
CAS:877399-52-5
Purity:≥99% HPLC Package:100kg;1kg;5kg - CB Index:58
- Related Information:Catalog(83)
- Company Name:Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd
- Tel:+86-0311-67591193 +86-15030197620
- Products Intro:Product Name:Crizotinib
CAS:877399-52-5
Purity:HPLC 99%+ Package:1KG;25KG;100KG More... - CB Index:58
- Related Information:Catalog(300)
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Crizotinib, 98%
CAS:877399-52-5
Purity:98% Package:10MG;250MG;50MG More... - CB Index:76
- Related Information:Catalog(94657)