TMC-207
843663-66-1 Basic informationMore
- Product Name:TMC-207
- Synonyms: TMC-207 R 207910 Bedaquiline(R 207910,TMC 207) Bedaquiline (TMC-207) (αS,βR)-Bedaquiline bedaquinline (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(methylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol Bedaquiline D6
- CAS:843663-66-1
- MF:C32H31BrN2O2
- MW:555.5
- EINECS:1308068-626-2
- Mol File:843663-66-1.mol
-
USE
Bedaquiline (also known as TMC207 and R207910) is a diarylquinoline that was discovered from a high-throughput, whole-cell screening strategy with Mycobacterium smegmatis used as a surrogate for M. tuberculosis. Bedaquiline is a single enantiomer of an initial screening hit. Bedaquiline has potent and selective activity against mycobacteria, and is active against both drug-sensitive and drug-resistant M. tuberculosis. The mechanism of action of bedaquiline is unique amongst anti-TB drugs and involves inhibition of mycobacterial ATP synthase; it is not active against human ATP synthase. Bedaquiline has in vivo activity in numerous preclinical models of TB infection, alone and in combination with other anti-TB agents, and has bactericidal activity in established TB infection models.
Lastest Price from TMC-207 manufacturers
- TMC-207
-
- US $32.00-1.30/KG
- CAS:843663-66-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- 2024-04-15
- Bedaquiline
-
- US $0.00 /g
- CAS:843663-66-1
- Min. Order: 1g
- Purity: 98% HPLC
- Supply Ability: 1kg
- 2024-03-12
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- Company Name:Shanghai Xiang Xin Industrial Co., Ltd.
- Tel:021-50211651 13651607026
- Products Intro:Product Name:bedaquinline
CAS:843663-66-1
Purity:99% Package:25mg,50mg,100mg. More... - CB Index:58
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- Company Name:Shanghai SynFarm Pharmaceutical Technology Co., Ltd.
- Tel:021-50793966 18917198199
- Products Intro:Product Name:Bedaquiline
CAS:843663-66-1
Purity:98%Min Package:10Mg,50Mg,100Mg,1g,10g More... - CB Index:58
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- Company Name:Twochem Co.Ltd.
- Tel:021-58111628 15800915896
- Products Intro:Product Name:TMC-207
CAS:843663-66-1
Purity:98%+ More... - CB Index:58
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- Company Name:ChengDu TongChuangYuan Pharmaceutical Co.Ltd
- Tel:028-83379370 13880556291
- Products Intro:Product Name:TMC-207
CAS:843663-66-1
Purity:99% HPLC Package:5KG;1KG More... - CB Index:58
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- Company Name:Cangzhou Enke Pharma-tech Co., Ltd.
- Tel:0317-5296180 15533709196
- Products Intro:Product Name:Bedaquiline (TMC-207)
CAS:843663-66-1
Purity:99% HPLCC 沧州恩科医药科技，大量现货，优势产品，欢迎询价下单，随时为您服务！ Package:1元/公斤 More... - CB Index:55
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- Company Name:AdooQ Bioscience CHINA
- Tel:025-58849295 18951903616;
- Products Intro:Product Name:Bedaquiline (TMC-207)
CAS:843663-66-1
Purity:0.98 Package:1mg;5mg;10mg;25mg;50mg;100mg More... - CB Index:60
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:(αS,βR)-Bedaquiline
CAS:843663-66-1
Package:100Mg,10Mg More... - CB Index:76
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