TMC-207

• Product Name:TMC-207
• Synonyms: TMC-207 R 207910 Bedaquiline(R 207910,TMC 207) Bedaquiline (TMC-207) (αS,βR)-Bedaquiline bedaquinline (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(methylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol Bedaquiline D6
• CAS:843663-66-1
• MF:C32H31BrN2O2
• MW:555.5
• EINECS:1308068-626-2
• Mol File:843663-66-1.mol
• 

Bedaquiline (also known as TMC207 and R207910) is a diarylquinoline that was discovered from a high-throughput, whole-cell screening strategy with Mycobacterium smegmatis used as a surrogate for M. tuberculosis. Bedaquiline is a single enantiomer of an initial screening hit. Bedaquiline has potent and selective activity against mycobacteria, and is active against both drug-sensitive and drug-resistant M. tuberculosis. The mechanism of action of bedaquiline is unique amongst anti-TB drugs and involves inhibition of mycobacterial ATP synthase; it is not active against human ATP synthase. Bedaquiline has in vivo activity in numerous preclinical models of TB infection, alone and in combination with other anti-TB agents, and has bactericidal activity in established TB infection models.

• Bedaquiline
• 
• US $0.00 /g
• CAS:843663-66-1
• Min. Order: 1g
• Purity: 99%min HPLC
• Supply Ability: 100G
• 2024-11-22

• Bedaquiline
• 
• US $0.00 /g
• CAS:843663-66-1
• Min. Order: 1g
• Purity: 98% HPLC
• Supply Ability: 1kg
• 2024-11-19

• Company Name:Shanghai Xiang Xin Industrial Co., Ltd.
• Tel:021-50211651 13651607026
• Products Intro:Product Name:bedaquinline
  CAS:843663-66-1
  Purity:99% Package:25mg,50mg,100mg. More...
• CB Index:58
• Related Information:Catalog(481)

• Company Name:Shanghai SynFarm Pharmaceutical Technology Co., Ltd.
• Tel:021-50793966 18917198199
• Products Intro:Product Name:Bedaquiline
  CAS:843663-66-1
  Purity:98%Min Package:10Mg,50Mg,100Mg,1g,10g More...
• CB Index:58
• Related Information:Catalog(280)

• Company Name:Cangzhou Enke Pharma-tech Co., Ltd.
• Tel:0317-5296180 15533709196
• Products Intro:Product Name:Bedaquiline (TMC-207)
  CAS:843663-66-1
  Purity:99%化工级沧州恩科医药科技，大量现货，优势产品，欢迎询价下单，随时为您服务！ Package:1元/公斤 More...
• CB Index:55
• Related Information:Catalog(1898)

• Company Name:J & K SCIENTIFIC LTD.
• Tel:010-82848833 400-666-7788
• Products Intro:Product Name:(αS,βR)-Bedaquiline
  CAS:843663-66-1
  Package:100Mg,10Mg More...
• CB Index:76
• Related Information:Catalog(96815)

• Company Name:Chembest Research Laboratories Limited
• Tel:+86-21-20908456
• Products Intro:Product Name:Bedaquiline(R 207910,TMC 207)
  CAS:843663-66-1
  Remarks:C13364 More...
• CB Index:61
• Related Information:Catalog(6005)

• Company Name:Beijing HwrkChemical Technology Co., Ltd
• Tel:010-89508211 18501085097
• Products Intro:Product Name:TMC-207
  CAS:843663-66-1
  Purity:99.00% Package:10g
• CB Index:55
• Related Information:Catalog(8418)