N-Methylleukotriene C4

• Product Name:N-Methylleukotriene C4
• Synonyms: N-[S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetren-1-yl]-N-(L-γ-glutamyl)-L-cysteinyl]-N-methylglycine N-Methylleukotriene C4 NMLTC4 N-METHYL LTC4 FPLBRCJNODNRQZ-UYCXAPQFSA-N Glycine, N-methyl-L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl- N methyl Leukotriene C4,N-methyl Leukotriene C-4,Nmethyl Leukotriene C4
• CAS:131391-65-6
• MF:C31H49N3O9S
• MW:639.81
• EINECS:
• Mol File:131391-65-6.mol
• 

Produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets, leukotriene C4 (LTC4) is the parent cysteinyl leukotriene formed by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity. LTC4, however, is rapidly metabolized to LTD4 and LTE4, which makes the characterization of LTC4 pharmacology difficult. N-methyl Leukotriene C4 (N-methyl LTC4) is a synthetic analog of LTC4 that is not readily metabolized to LTD4 and LTE4.It acts as a potent and selective CysLT2 receptor agonist exhibiting EC50 values of 122 and > 2,000 nM at the human CysLT2 and CysLT1 receptors, respectively. It has essentially the same potency as LTC4 at both the human and murine receptors CysLT2 receptors. N-methyl LTC4 is potent and active in vivo, causing vascular leak in mice overexpressing the human CysLT2 receptor but not in CysLT2 receptor knockout mice.

• Company Name:Energy Chemical
• Tel:021-58432009 400-005-6266
• Products Intro:Product Name:N-methylLeukotrieneC4
  CAS:131391-65-6
  Purity:NULL Package:25g;50g Remarks:NULL
• CB Index:58
• Related Information:Catalog(44843)

• Company Name:TargetMol Chemicals Inc.
• Tel: 4008200310
• Products Intro:Product Name:N-methyl Leukotriene C4;N methyl Leukotriene C4,N-methyl Leukotriene C-4,Nmethyl Leukotriene C4
  CAS:131391-65-6
  Purity:98% Package:1 mg
• CB Index:58
• Related Information:Catalog(24017)

• Company Name:Shanghai Yifei Biotechnology Co. , Ltd.
• Tel:021-65675885 18964387627
• Products Intro:Product Name:N-methyl Leukotriene C4
  CAS:131391-65-6
  Purity:97% Package:25μg;50μg;100μg
• CB Index:58
• Related Information:Catalog(8740)

• Company Name:Beijing Zhijie Fangyuan Technology Co., Ltd.
• Tel:010-82897201 15810200961
• Products Intro:Product Name:N-methyl Leukotriene C4
  CAS:131391-65-6
  
• CB Index:58
• Related Information:Catalog(6984)

• Company Name:Beijing Bolide Biotechnology Co., Ltd.
• Tel:010-51653916
• Products Intro:Product Name:N-methyl Leukotriene C4
  CAS:131391-65-6
  
• CB Index:58
• Related Information:Catalog(6172)