Basic information Supplier

N-Methylleukotriene C4

Basic information Supplier
131391-65-6 Basic informationMore
USE
Produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets, leukotriene C4 (LTC4) is the parent cysteinyl leukotriene formed by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity. LTC4, however, is rapidly metabolized to LTD4 and LTE4, which makes the characterization of LTC4 pharmacology difficult. N-methyl Leukotriene C4 (N-methyl LTC4) is a synthetic analog of LTC4 that is not readily metabolized to LTD4 and LTE4.It acts as a potent and selective CysLT2 receptor agonist exhibiting EC50 values of 122 and > 2,000 nM at the human CysLT2 and CysLT1 receptors, respectively. It has essentially the same potency as LTC4 at both the human and murine receptors CysLT2 receptors. N-methyl LTC4 is potent and active in vivo, causing vascular leak in mice overexpressing the human CysLT2 receptor but not in CysLT2 receptor knockout mice.

Browse by Nationality 131391-65-6 Suppliers >Global suppliers

Beijing (4) Shanghai (9) Guangdong (2) Anhui (1) Other (2) Member (18) All (18)
Please select the suppliers
Recommend You Select Member Companies
  • Company Name:ChemeGen(Shanghai) Biotechnology Co.,Ltd.
  • Tel: 18818260767
  • Products Intro:Product Name:N-methyl Leukotriene C4
    CAS:131391-65-6
    Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
  • CB Index:58
  • Related Information:Catalog(11218)
  •  
  • Company Name:Energy Chemical
  • Tel:021-58432009 400-005-6266
  • Products Intro:Product Name:N-methylLeukotrieneC4
    CAS:131391-65-6
    Purity:NULL Package:25g;50g Remarks:NULL
  • CB Index:58
  • Related Information:Catalog(44807)
  •  
  • Company Name:Shanghai Universal Biotech Co.,Ltd
  • Tel: 13774214275
  • Products Intro:Product Name:N-methyl Leukotriene C4
    CAS:131391-65-6
    Package:25ug Remarks: 见优宁维官网
  • CB Index:58
  • Related Information:Catalog(24998)
  •  
  • Company Name:TargetMol Chemicals Inc.
  • Tel: 4008200310
  • Products Intro:Product Name:N-methyl Leukotriene C4
    CAS:131391-65-6
    Package:50μg/RMB 5470
  • CB Index:58
  • Related Information:Catalog(24644)
  •  
  • Company Name:Shanghai Yifei Biotechnology Co. , Ltd.
  • Tel:021-65675885 18964387627
  • Products Intro:Product Name:N-methyl Leukotriene C4
    CAS:131391-65-6
    Purity:97% Package:25μg;50μg;100μg
  • CB Index:58
  • Related Information:Catalog(11974)
  •  
  • Company Name:Neobioscience Co., Ltd.
  • Tel:4006-800-892
  • Products Intro:Product Name:N-methyl Leukotriene C4
  • CB Index:58
  • Related Information:Catalog(6682)
  •  
  • Company Name:Absin Bioscience Inc.
  • Tel:021-38015121
  • Products Intro:
  • CB Index:58
  • Related Information:Catalog(6705)
  •  
1 2 3