Dovitinib

• Product Name:Dovitinib
• Synonyms: 4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one dovitinib Unii-I35H55G906 CHIR258 7.7G TKI-258 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one CHIR-258(Dovitinib,TKI258) CHIR-258(Dovitinib)
• CAS:405169-16-6
• MF:C21H21FN6O
• MW:392.43
• EINECS:1308068-626-2
• Mol File:405169-16-6.mol
• 

<p>Dovitinib is a receptor tyrosine kinase inhibitor that targets vascular endothelial growth factor-2, basic fibroblast growth factor-1, and platelet-derived growth factor β receptors (IC50s = 65, 11, and 5 nM, respectively). At 0.04 μM, dovitinib can inhibit endothelial cell proliferation and motility. These antiangiogenic effects have been proposed to be the mechanism by which dovitinib inhibits hepatocellular carcinoma growth and metastasis. Dovitinib has been evaluated in clinical trials for the treatment of advanced solid tumors.</p> <p>Dovitinib is a receptor tyrosine kinase inhibitor that targets vascular endothelial growth factor-2, basic fibroblast growth factor-1, and platelet-derived growth factor β receptors (IC50s = 65, 11, and 5 nM, respectively). At 0.04 μM, dovitinib can inhibit endothelial cell proliferation and motility. These antiangiogenic effects have been proposed to be the mechanism by which dovitinib inhibits hepatocellular carcinoma growth and metastasis. Dovitinib has been evaluated in clinical trials for the treatment of advanced solid tumors.</p>

• Dovitinib
• 
• US $0.00-0.00/kg
• CAS:405169-16-6
• Min. Order: 1kg
• Purity: 99%, Single impurity＜0.1
• Supply Ability: 1 ton
• 2024-11-26

• Company Name:Tianjin Kailiqi Biotechnology Co., Ltd.
• Tel: 15076683720
• Products Intro:Product Name:CHIR-258(Dovitinib,TKI258)
  CAS:405169-16-6
  Purity:>98% Package:2g Remarks:2g More...
• CB Index:55
• Related Information:Catalog(4596)

• Company Name:Minglong (Xianning) Pharmaceutical Co., LTD
• Tel:155-7155-6913 15571556913
• Products Intro:Product Name:2(1H)-Quinolinone,4-aMino-5-fluoro-3-[5-(4-Methyl-1-piperazinyl)-1H-benziMidazol-2-yl]- (9CI)
  CAS:405169-16-6
  Purity:99 Package:1MG~G~KG~T/RMB 1;1MG~G~KG~T/RMB 1;1MG~G~KG~T/RMB 1
• CB Index:58
• Related Information:Catalog(2620)

• Company Name:ZHIWE CHEMTECH CO LTD
• Tel:021-20221225 13917446399
• Products Intro:Product Name:Dovitinib
  CAS:405169-16-6
  More...
• CB Index:61
• Related Information:Catalog(627)

• Company Name:Chembest Research Laboratories Limited
• Tel:+86-21-20908456
• Products Intro:Product Name:CHIR-258(Dovitinib,TKI258)
  CAS:405169-16-6
  Remarks:C13463 More...
• CB Index:61
• Related Information:Catalog(6005)