4-AMINO-1,8-NAPHTHALIMIDE
1742-95-6 Basic informationMore
- Product Name:4-AMINO-1,8-NAPHTHALIMIDE
- Synonyms: 4-Amino-1,8-naphthalenedicarbimide 4-Amino-1,8-naphthalenedicarboximide 4-Aminonaphthalene-1,8-dicarbimide 6-Amino-2,3-dihydro-1H-benzo[de]isoquinoline-1,3-dione 6-Amino-2H-benzo[de]isoquinoline-1,3-dione 4-Amino-1,8-naphthalimide,98% 6-amino-1h-benz(de)isoquinoline-3(2h)-dione 6-amino-1h-benz[de]isoquinoline-3(2h)-dione
- CAS:1742-95-6
- MF:C12H8N2O2
- MW:212.2
- EINECS:217-110-1
- Mol File:1742-95-6.mol
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USE
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. 4-amino-1,8-Naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM). It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation, although it is not cytotoxic in the absence of radiation. 4-ANI is used to study the role of PARP activity in various cell systems.
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- Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel:4006608290; 18621169109
- Products Intro:Product Name:4-AMino-1,8-naphthaliMide
CAS:1742-95-6
Purity:98% Remarks:10413 More... - CB Index:62
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:4-AMINO-1,8-NAPHTHALIMIDE
CAS:1742-95-6
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
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- Company Name:Shandong Xiya Chemical Co., Ltd
- Tel:13355009207 13355009207
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Purity:>=98.0% Package:50MG - CB Index:57
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- Products Intro:Product Name:4-AMINO-1,8-NAPHTHALIMIDE
CAS:1742-95-6
Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg More... - CB Index:57
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- Company Name:Guangzhou Isun Pharmaceutical Co., Ltd
- Tel:020-39119399 18927568969
- Products Intro:Product Name:4-AMino-1,8-naphthaliMide
CAS:1742-95-6
Purity:>=98.0% Package:25Mg; 1g; 100g; 500g More... - CB Index:55
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- Company Name:Suzhou yacoo science co.,Ltd
- Tel:0512-87182056 18013166090
- Products Intro:Product Name:4-AMINO-1,8-NAPHTHALIMIDE
CAS:1742-95-6
Purity:99% Package:10g;50g;1kg;5Kg;25kg; - CB Index:60
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- Company Name:Shanghai Tombiopharma Chemical Co. Ltd.
- Tel: 13391076197
- Products Intro:Product Name:4-AMINO-1,8-NAPHTHALIMIDE
CAS:1742-95-6
Package:1g/ - CB Index:55
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