CARBACYCLIN

• Product Name:CARBACYCLIN
• Synonyms: 6,9ALPHA-METHYLENE-11ALPHA,15S-DIHYDROXY-PROSTA-5E,13E-DIEN-1-OIC ACID 6A-CARBA-PROSTAGLANDIN I2 carboprostacyclin 6,9-Methanoprostaglandin I2 6a-Carba-prostaglandinI2, CarbocyclicPGI2 (5E)-6a-Carbaprostaglandin 12 5-[(1β,3E,5β,6R)-6β-[(1E,3S)-3-Hydroxy-1-octenyl]-7α-hydroxybicyclo[3.3.0]octane-3-ylidene]pentanoic acid 5-[(2E,3aS,5R,6aβ)-Octahydro-5α-hydroxy-4β-[(1E,3S)-3-hydroxy-1-octenyl]pentalen-2-ylidene]pentanoic acid
• CAS:69552-46-1
• MF:C21H34O4
• MW:350.49
• EINECS:636-209-4
• Mol File:69552-46-1.mol
• 

<p>Carbacyclin is a stable analog of PGI2. When infused in rabbits or dogs, it inhibits ex vivo platelet aggregation, but the effect persists only 10 minutes after termination of the infusion. Carbacyclin is a stable analog of PGI2. Carbacyclin inhibits platelet aggregation with 10% of the molar potency exhibited by PGI2. The ED50 of Carbacyclin for the in vitro inhibition of ADP-induced platelet aggregation in human PRP is 47 nM. It was also shown to effect terminal differentiation of preadipose into adipose cells and enhance the expression of angiotensinogen and adipose fatty acid binding protein with an EC50 of about 0.5 μM.</p>

• Company Name:MedBioPharmaceutical Technology Inc
• Tel:021-69568360 18916172912
• Products Intro:Product Name:CARBACYCLIN
  CAS:69552-46-1
  Purity:98% Package:1mg; 5mg; 500ug Remarks:Medbio
• CB Index:58
• Related Information:Catalog(8141)