Teniposide
29767-20-2 Basic informationMore
- Product Name:Teniposide
- Synonyms: (5R,5aα)-5α,8,8aβ,9β-Tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[[4-O,6-O-[(R)-2-thienylmethylene]-β-D-glucopyranosyl]oxy]furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one 4'-Demethylepipodophyllotoxin-9-(4,6-O-2-thenylidene β-D-glucopyranoside) 4’-Demethylepipodophyllotoxin9-(4,6-o-2-thenylidene- 4'-Demethylepipodophyllotoxin thenylidene glucoside Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-o-2-thienylidene-.beta.-D-glucopyranoside) Furo[3',4':6,7]naphtho[2,3-D]-1,3-dioxol-6(5ah)-one, 5,8,8A,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-o-(2-thienylmethylene)-.beta.-D-glucopyranosyl]oxy]-, [5R-(5.alpha.,5A.beta.,8A.alpha.,9.beta.)]- (10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-(thiophen-2-yl)-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-diMethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one Teniposide(VuMon)
- CAS:29767-20-2
- MF:C32H32O13S
- MW:656.65
- EINECS:249-831-2
- Mol File:29767-20-2.mol
-
USE
Teniposide is available in 50-mg ampules with Cremophor ELfor IV administration in the treatment of acute lymphoblasticleukemia (ALL). The agent is more potent as an inhibitor oftopoisomerase II. The pharmacokinetics of teniposide issimilar to that of etoposide; however, the more lipophilic teniposideis more highly protein bound (99%) and less isexcreted unchanged in the urine (10%–20%). There is alsogreater overall metabolism of teniposide; however, CYP3A4-mediated conversion to the active catechol is slower comparedwith etoposide. Elimination occurs primarily in the urine witha terminal elimination half-life of 5 hours.
Lastest Price from Teniposide manufacturers
- Teniposide
-
- US $0.00 /Kg/Bag
- CAS:29767-20-2
- Min. Order: 10g
- Purity: 98%min
- Supply Ability: 10kg
- 2023-11-15
- Teniposide
-
- US $15.00-10.00/KG
- CAS:29767-20-2
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- 2021-08-12
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Teniposide, 98%
CAS:29767-20-2
Purity:98% Package:1G More... - CB Index:76
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:Teniposide
CAS:29767-20-2
Purity:98% HPLC Package:1g;5g;25g;100g More... - CB Index:69
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- Company Name:Chembest Research Laboratories Limited
- Tel:021-20908456
- Products Intro:Product Name:Teniposide(VM-26)
CAS:29767-20-2
Purity:99% Package:500mg;1g;5g;10g;50g;100g;500g;1kg Remarks:C14237 More... - CB Index:61
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- Company Name:TCI (Shanghai) Development Co., Ltd.
- Tel:021-67121386
- Products Intro:Product Name:Teniposide
CAS:29767-20-2
Purity:98.0% LC Package:100MG,20MG More... - CB Index:81
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- Company Name:Hangzhou Yuhao Chemical Technology Co., Ltd
- Tel:0571-82693216
- Products Intro:Product Name:Teniposide
CAS:29767-20-2
More... - CB Index:52
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- Company Name:Dalian Meilun Biotech Co., Ltd.
- Tel:0411-62910999 13889544652
- Products Intro:Product Name:Teniposide
CAS:29767-20-2
Purity:>98%,BR Package:100MG Remarks:MB1236 More... - CB Index:58
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