BuforMin Hydrochloride
1190-53-0 Basic informationMore
- Product Name:BuforMin Hydrochloride
- Synonyms: 1-Butylbigyanidine hydrochloride 1-Butylbiguanide Hydrochloride N-ButylidodicarboniMidic DiaMide Hydrochloride PanforMin Sindiatil TideMol Ziavetine Adebit
- CAS:1190-53-0
- MF:C6H16ClN5
- MW:193.68
- EINECS:214-723-6
- Mol File:1190-53-0.mol
USE
Buformin is a biguanide derivative with antihyperglycemic activity. It delays absorption of glucose from the gastrointestinal tract, increases insulin sensitivity and glucose utilization in peripheral cells, and inhibits hepatic gluconeogenesis. It can also deactivate the glycolytic pathway by suppressing glyceraldehyde 3-phosphate dehydrogenase gene expression, which can lead to lactic acidosis. Biguanides, such as buformin, are reported to inhibit the mitochondrial respiratory complex I by inhibiting ubiquinone reduction and by stimulating reactive oxygen species production via the complex I flavin. Some biguanides, including buformin, can also inhibit the mitochondrial ATP synthase. Buformin has also been examined for antitumor activity due to its ability to disrupt the unfolded protein response transcription program during glucose deprivation, which induces cell death in glucose-deprived tumor cells.<p>BuforMin Hydrochloride is a biguanide derivative with antihyperglycemic activity. It delays absorption of glucose from the gastrointestinal tract, increases insulin sensitivity and glucose utilization in peripheral cells, and inhibits hepatic gluconeogenesis. BuforMin Hydrochloride has also been examined for antitumor activity due to its ability to disrupt the unfolded protein response transcription program during glucose deprivation, which induces cell death in glucose-deprived tumor cells.</p>
Lastest Price from BuforMin Hydrochloride manufacturers
- BuforMin Hydrochloride
- US $0.00-0.00/g
- CAS:1190-53-0
- Min. Order: 10g
- Purity: 98%Min
- Supply Ability: 1000kg
- 2023-03-16
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Buformin hydrochloride, 95%
CAS:1190-53-0
Purity:95% Package:100MG More... - CB Index:76
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- Company Name:Adamas Reagent, Ltd.
- Tel:400-6009262 16621234537
- Products Intro:Product Name:Buformin Hydrochloride
CAS:1190-53-0
Purity:98% Package:100mg;250mg;1g - CB Index:59
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- Company Name:Nanjing Chemlin Chemical Co., Ltd
- Tel:025-83697070
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CAS:1190-53-0
Purity:98% Package:5KG; 1KG - CB Index:64
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- Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel:400-400-6206333 18521732826
- Products Intro:Product Name:Buformin Hydrochloride
CAS:1190-53-0
Purity:95% Package:250mg/RMB 2426.00;50mg/RMB 671.90;100mg/RMB 1137.90 - CB Index:65
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- Company Name:ShangHai Caerulum Pharma Discovery Co., Ltd.
- Tel:18149758185 18149758185
- Products Intro:Product Name:Buformin hydrochloride
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Purity:98% Package:1g;10g;100g - CB Index:58
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- Company Name:Alta Scientific Co., Ltd.
- Tel:022-6537-8550 15522853686
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- Company Name:Shanghai YuanYe Biotechnology Co., Ltd.
- Tel:021-61312847; 18021002903
- Products Intro:Product Name:Butyl-Biguanide Hydrochloride
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Purity:Purity≥95% Package:50mg - CB Index:60
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