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PENICILLIC ACID

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USE
Gram negative bacteria utilize N-acylated homoserine lactones to coordinate expression of virulence in response to the density of the surrounding bacterial population in a process termed quorum sensing. By interfering with this communication and thereby disrupting virulence expression, quorum sensing inhibitors are emerging as an alternative to the conventional ways of fighting bacterial infections. Penicillic acid is a mycotoxin produced from Penicillium species identified in molds on corn and other grains. At 80 μM, penicillic acid inhibits bacterial quorum sensing communication in P. aeruginosa by selectively repressing various virulence factor and other quorum sensing-regulated genes. It has been shown to inhibit Fas-mediated apoptosis at 100-200 μM by targeting caspase-8 activity in Burkitt’s lymphoma Raji cells.
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  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:010-82848833 400-666-7788
  • Products Intro:Product Name:Penicillic acid, 99%
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    Purity:99% Package:25MG;5MG More...
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  • Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
  • Tel:021-61259108 18621169085
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    Purity:99% Remarks:22927 More...
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  • Company Name:ChemStrong Scientific Co.,Ltd
  • Tel:0755-0755-66853366 13670046396
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    Purity:95% HPLC Package:10mg;25mg;50mg;100mg More...
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  • Company Name:Shanghai EFE Biological Technology Co., Ltd.
  • Tel:021-65675885 18964387627
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    Purity:98% Package:5mg;10mg;25mg More...
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  • Company Name:Shanghai YuanYe Biotechnology Co., Ltd.
  • Tel:021-61312847; 18021002903
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    Purity:HPLC≥98% Package:5mg
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  • Company Name:Shandong Xiya Chemical Co., Ltd.
  • Tel:4009903999 13395398332
  • Products Intro:CAS:90-65-3
    Purity:>=98.0% (HPLC) Package:10mg;50mg
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