MK-2 Inhibitor III
1186648-22-5 Basic informationMore
- Product Name:MK-2 Inhibitor III
- Synonyms: MK-2 Inhibitor III 2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one:hydrate MK-2 INHIBITOR III (COMPOUND 16) MK-2 Inhibitor III - CAS 1186648-22-5 - Calbiochem MK2-IN-3 hydrate 2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate Inhibitor,MAP kinase activated protein kinase 2,inhibit,MK2 IN 3 hydrate,MAPKAP kinase 2,MK-2-IN-3 hydrate,MAPK activated protein kinase 2,MK2IN3 hydrate,MAPKAPK2 (MK2),Mitogen-activated protein kinase activated protein kinase 2
- CAS:1186648-22-5
- MF:C21H18N4O2
- MW:358.4
- EINECS:
- Mol File:1186648-22-5.mol
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USE
MAP kinase-activated protein kinase 2 (MAPKAP2, MK2) is a stress-activated serine/threonine protein kinase that is phosphorylated by p38 MAP kinase and is involved in diverse cellular functions with a central role in inflammation. MK2 inhibitor III is a potent, cell-permeable inhibitor of MK2 (IC50 = 8.5 nM). It less potently blocks MK3 and MK5 (IC50s = 210 and 81 nM, respectively) and is weak or inactive against several other kinases, including other p38 MAP kinase targets. MK2 inhibitor III prevents LPS-induced synthesis of TNF-α in human monocyte-like U937 cells (IC50 = 4.4 μM).[Cayman Chemical]
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- Company Name:Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel: 15076683720
- Products Intro:Product Name:MK2 Inhibitor III
CAS:1186648-22-5
Purity:≥98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only. - CB Index:55
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- Company Name:ShangHai Biochempartner Co.,Ltd
- Tel:17754423994 17754423994
- Products Intro:Product Name:MK2-IN-3 hydrate
CAS:1186648-22-5
Purity:98% HPLC LCMS Package:100MG;1G - CB Index:62
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- Company Name:MedBioPharmaceutical Technology Inc
- Tel:021-69568360 18916172912
- Products Intro:Product Name:MK-2 Inhibitor III
CAS:1186648-22-5
Purity:98% Package:5mg; 500ug; 1mg Remarks:Medbio - CB Index:58
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- Company Name:cjbscvictory
- Tel:13348960310 13348960310
- Products Intro:Product Name:MK-2 Inhibitor III
CAS:1186648-22-5
Purity:98% Package:5mg；10mg；20mg；50mg；100mg；200mg - CB Index:58
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