Lorlatinib

• Product Name:Lorlatinib
• Synonyms: (10R)-7-Amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-2H-4,8-methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile Lorlatinib,PF-06463922 PF-06463922, Lorlatinib (R)-26-amino-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-15-carbonitrile Lorlatinib(PF0643922) High Purity API Lorlatinib Anaplastic lymphoma kinase (ALK) Lorlatinib Powder
• CAS:1454846-35-5
• MF:C21H19FN6O2
• MW:406.41
• EINECS:813-704-5
• Mol File:1454846-35-5.mol
• 

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that promotes cell proliferation and blocks apoptosis. PF-06463922 is an ATP-competitive, selective inhibitor of ALK (Ki = < 0.07 nM) and c-Ros oncogene 1 (ROS1, Ki = 0.7 nM). It has strong activity against all known ALK and ROS1 mutants identified in patients, including the EML4-L1196M mutant of ALK (Ki = < 0.02 nM). PF-06463922 is orally available, displaying inhibition of ALK phosphorylation and antitumor efficacy in a xenograft model expressing EML4-L1196M ALK. It demonstrates efficient blood-brain barrier penetration, produces brain tumor regression in mice harboring EML4-ALK tumors, and increases overall survival.[Cayman Chemical]

• Lorlatinib
• 
• US $0.00-0.00/kg
• CAS:1454846-35-5
• Min. Order: 1kg
• Purity: 99%，single impurity＜0.1
• Supply Ability: 1 ton
• 2024-11-21

• Lorlatinib
• 
• US $0.00 /g
• CAS:1454846-35-5
• Min. Order: 1g
• Purity: More Than 99%
• Supply Ability: 50kg/Month
• 2024-11-18

• Company Name:Suzhou Ryan Pharmaceutical Technology Co., Ltd.
• Tel:0512-68780025 18962125825
• Products Intro:Product Name:Lorlatinib
  CAS:1454846-35-5
  Purity:99% Package:1kg;10kg More...
• CB Index:62
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• Company Name:Shanghai Hope Chem Co., Ltd.，
• Tel:+21-18501659228 18501659228
• Products Intro:Product Name:Lorlatinib
  CAS:1454846-35-5
  Purity:99.5%+ Remarks:1kg~10kg More...
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• Company Name:Liuyang huarui material technology co., ltd.
• Tel: 13467605171
• Products Intro:Product Name:Lorlatinib
  CAS:1454846-35-5
  Purity:99% Package:1kg/Bag
• CB Index:58
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• Company Name:Hangzhou Chemtrue Bio-Tech Co.,Ltd.
• Tel:0571-86828652 18857119830
• Products Intro:Product Name:Lorlatinib
  CAS:1454846-35-5
  Purity:99% HPLC Package:100g;1KG;5KG;25KG
• CB Index:58
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• Company Name:Anqing Benro pharmachem Technology Co.,Ltd.
• Tel:05565209906 15391842992
• Products Intro:Product Name:Loratinib
  CAS:1454846-35-5
  Purity:99% Package:1g/RMB 100
• CB Index:58
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• Company Name:Shanghai Zhen Li Biological Technology Co., Ltd
• Tel:021-16621358918; 18516310516
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  CAS:1454846-35-5
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• Company Name:Changzhou Borl Biotechnology Co.,LTD
• Tel: 13606124132;13656121842
• Products Intro:Product Name: Lorlatinib
  CAS:1454846-35-5
  Purity:>99.0% Package:1g
• CB Index:58
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• Company Name:Chunchuang (Wuhan) Technology Co., Ltd
• Tel: 15342225168
• Products Intro:Product Name:Lorlatinib (PF-06463922)
  CAS:1454846-35-5
  Purity:99.9+HPLC Package:1mg;1g;10g;100g;1kg;10kg;100kg;1T
• CB Index:58
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