TAK 599
400827-46-5 Basic informationMore
- Product Name:TAK 599
- Synonyms: TAK 599 Ceftaroline fosaMil PPI 0903 TAK-599 (ceftaroline fosamil) Ceftaroline Fosamil Acetate C22H22N8O8PS4. C2H3O2 TAK-599; CEFTAROLINE FOSAMIL;TAK599; TAK 599;PPI-0903;PPI0903;PPI 0903 Ceftaroline fosamil acetate salt
- CAS:400827-46-5
- MF:C24H25N8O10PS4
- MW:744.72
- EINECS:
- Mol File:400827-46-5.mol
USE
Ceftaroline fosamil, also referred to as TAK-599, is a cephalosporin
antibacterial agent that was approved in the United States in October
2010 for the IV treatment of acute bacterial skin and skin structure infections
(ABSSSI) and community-acquired bacterial pneumonia (CABP).
Ceftaroline fosamil is the water-soluble, N-phosphono prodrug of ceftaroline
(T-91825), a broad-spectrum, bactericidal agent with potent activity
against methicillin-resistant Staphylococcus aureus (MRSA) strains, multidrug
resistant S. pneumonia, and common gram-negative organisms.
Ceftaroline binds to PBP2a as well as other PBPs with high
affinity and, as a result, retains potent activity. Ceftaroline exhibits activity
against most gram-positive pathogens, including β-lactam-susceptible
and -resistant S. aureus, vancomycin-resistant S. aureus, and resistant and
susceptible forms of S. pneumoniae but has weak activity against Enterococcus
sp. The gram-negative antibacterial activity of ceftaroline is limited mainly
to respiratory pathogens such as Moraxella catarrhalis and Haemophilus influenzae.
Lastest Price from TAK 599 manufacturers
- Ceftaroline fosamil acetate
- US $0.00 /G
- CAS:400827-46-5
- Min. Order: 1G
- Purity: 98%min
- Supply Ability: 30kg/month
- 2024-12-13
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- Company Name:Nanjing Sunlida Biological Technology Co., Ltd.
- Tel:025-57798810
- Products Intro:CAS:400827-46-5
Purity:98% Package:1g;5g;25g;100g - CB Index:55
- Related Information:Catalog(3239)
- Company Name:Suzhou yacoo science co.,Ltd
- Tel:0512-87182056 18013166090
- Products Intro:Product Name:TAK 599
CAS:400827-46-5
Purity:99% Package:10g;50g;1kg;5Kg;25kg; - CB Index:60
- Related Information:Catalog(7295)
- Company Name:Shanghai Kewel Chemical Co., Ltd.
- Tel:021-64609169 18901607656
- Products Intro:Product Name:Ceftaroline Fosamil Acetate
CAS:400827-46-5
Purity:95+ HPLC; Package:10mg;25mg;50mg;100mg - CB Index:50
- Related Information:Catalog(9906)