GW1929
196808-24-9 Basic informationMore
- Product Name:GW1929
- Synonyms: GW1929 GW1929 HYDRATE N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrate (2S)-2-(2-benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid (S)-2-(2-Benzoylphenylamino)-3-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)phenyl)propanoic acid GW 1929 hydrochloride N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosinehydrochloride N-(2-BENZOYLPHENYL)-O-[2-(METHYL-2-PYRIDINYLAMINO)ETHYL]-L-TYROSINE
- CAS:196808-24-9
- MF:C30H29N3O4
- MW:495.57
- EINECS:
- Mol File:196808-24-9.mol
-
USE
Peroxisome proliferator-activated receptor (PPAR) γ is a nuclear receptor that, when activated, regulates fatty acid storage and glucose metabolism. The best known class of PPARγ ligands are the thiazolidinediones, including troglitazone and rosiglitazone . GW 1929 is a non-thiazolidinedione activator of PPARγ that binds with a Ki value of 1.4 nM, with greater than 1,000-fold selectivity over other PPAR subtypes. It has anti-hyperglycemic and anti-hyperlipidemic activity when given orally in mouse and rat models of type 2 diabetes. Both in vitro and in vivo effects of GW 1929 on PPARγ greatly exceed those produced by troglitazone. In addition, GW 1929 has neuroprotective effects in global cerebral ischemic-reperfusion injury that are related to reduced inflammation and apoptotic DNA fragmentation.[Cayman Chemical]
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- Company Name:Beijing Jin Ming Biotechnology Co., Ltd.
- Tel:010-60605840 18892239720
- Products Intro:Product Name:GW1929
CAS:196808-24-9
Purity:98%（HPLC） Package:100mg;25mg;5mg More... - CB Index:58
- Related Information:Catalog(12306)
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:GW 1929 hydrochloride;N-(2-Benzoylphenyl)-O-[2-(Methyl-2-pyridinylaMino)ethyl]-L-tyrosinehydrochloride
CAS:196808-24-9
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
- Related Information:Catalog(15839)
- Company Name:Shanghai Tauto Biotech Co., Ltd.
- Tel:021-51320588
- Products Intro:Product Name:GW1929
CAS:196808-24-9
Purity:NLT 95% HPLC Package:10Mg;20Mg;50Mg;100Mg to graMs.Not More than tens of graMs. Remarks:AG-CR1-0116-M025 More... - CB Index:66
- Related Information:Catalog(3989)
- Company Name:Sigma-Aldrich
- Tel:021-61415566 800-8193336
- Products Intro:Product Name:GW1929 hydrate
CAS:196808-24-9
Purity:>98% (HPLC), solid Package:25MG Remarks:G5668-25MG More... - CB Index:80
- Related Information:Catalog(51456)