GW1929
196808-24-9 Basic informationMore
- Product Name:GW1929
- Synonyms: GW1929 GW1929 HYDRATE N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrate (2S)-2-(2-benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid (S)-2-(2-Benzoylphenylamino)-3-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)phenyl)propanoic acid GW 1929 hydrochloride N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosinehydrochloride N-(2-BENZOYLPHENYL)-O-[2-(METHYL-2-PYRIDINYLAMINO)ETHYL]-L-TYROSINE
- CAS:196808-24-9
- MF:C30H29N3O4
- MW:495.57
- EINECS:
- Mol File:196808-24-9.mol
-
USE
Peroxisome proliferator-activated receptor (PPAR) γ is a nuclear receptor that, when activated, regulates fatty acid storage and glucose metabolism. The best known class of PPARγ ligands are the thiazolidinediones, including troglitazone and rosiglitazone . GW 1929 is a non-thiazolidinedione activator of PPARγ that binds with a Ki value of 1.4 nM, with greater than 1,000-fold selectivity over other PPAR subtypes. It has anti-hyperglycemic and anti-hyperlipidemic activity when given orally in mouse and rat models of type 2 diabetes. Both in vitro and in vivo effects of GW 1929 on PPARγ greatly exceed those produced by troglitazone. In addition, GW 1929 has neuroprotective effects in global cerebral ischemic-reperfusion injury that are related to reduced inflammation and apoptotic DNA fragmentation.[Cayman Chemical]
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- Company Name:Nanjing Yiming Pharmaceutical Technology Co., Ltd.
- Tel:19850700912; 19850700912
- Products Intro:Product Name:GW1929
CAS:196808-24-9
Purity:98%，99%；异构体纯度98%+ Package:10mg;1g;10g - CB Index:58
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- Company Name:Shanghai Shengxiu Biotechnology Co., Ltd.
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Purity:97% Package:5g ;10g - CB Index:58
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- Company Name:Beijing Jin Ming Biotechnology Co., Ltd.
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CAS:196808-24-9
Purity:>=98%（HPLC） Package:1mL - CB Index:58
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
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- Products Intro:Product Name:GW 1929 hydrochloride;N-(2-Benzoylphenyl)-O-[2-(Methyl-2-pyridinylaMino)ethyl]-L-tyrosinehydrochloride
CAS:196808-24-9
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
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- Company Name:NCE Biomedical Co.,Ltd.
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- Products Intro:Product Name:GW1929
CAS:196808-24-9
Purity:99% HPLC Package:50Mg,100Mg,500Mg,1g,5g,10g,50g,100g,500g,1kg Remarks:XYA0928 More... - CB Index:55
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- Company Name:Haoyuan Chemexpress Co., Ltd.
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CAS:196808-24-9
Purity:>98% Package:950RMB/5mg More... - CB Index:61
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- Company Name:Shanghai Tauto Biotech Co., Ltd.
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CAS:196808-24-9
Purity:NLT 95% HPLC Package:10Mg;20Mg;50Mg;100Mg to graMs.Not More than tens of graMs. Remarks:AG-CR1-0116-M025 More... - CB Index:66
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- Company Name:AdooQ Bioscience CHINA
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- Products Intro:Product Name:GW1929
CAS:196808-24-9
Purity:0.98 Package:1mg;5mg;10mg;25mg;50mg;100mg More... - CB Index:60
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