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GW1929

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Peroxisome proliferator-activated receptor (PPAR) γ is a nuclear receptor that, when activated, regulates fatty acid storage and glucose metabolism. The best known class of PPARγ ligands are the thiazolidinediones, including troglitazone and rosiglitazone . GW 1929 is a non-thiazolidinedione activator of PPARγ that binds with a Ki value of 1.4 nM, with greater than 1,000-fold selectivity over other PPAR subtypes. It has anti-hyperglycemic and anti-hyperlipidemic activity when given orally in mouse and rat models of type 2 diabetes. Both in vitro and in vivo effects of GW 1929 on PPARγ greatly exceed those produced by troglitazone. In addition, GW 1929 has neuroprotective effects in global cerebral ischemic-reperfusion injury that are related to reduced inflammation and apoptotic DNA fragmentation.[Cayman Chemical]
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  • Company Name:Beijing Jin Ming Biotechnology Co., Ltd.
  • Tel:010-60605840 18892239720
  • Products Intro:Product Name:GW1929
    CAS:196808-24-9
    Purity:98%(HPLC) Package:100mg;25mg;5mg More...
  • CB Index:58
  • Related Information:Catalog(12308)
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  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:821-50328103-801 18930552037
  • Products Intro:Product Name:GW 1929 hydrochloride;N-(2-Benzoylphenyl)-O-[2-(Methyl-2-pyridinylaMino)ethyl]-L-tyrosinehydrochloride
    CAS:196808-24-9
    Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More...
  • CB Index:69
  • Related Information:Catalog(15848)
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  • Company Name:Shanghai Tauto Biotech Co., Ltd.
  • Tel:021-51320588
  • Products Intro:Product Name:GW1929
    CAS:196808-24-9
    Purity:NLT 95% HPLC Package:10Mg;20Mg;50Mg;100Mg to graMs.Not More than tens of graMs. Remarks:AG-CR1-0116-M025 More...
  • CB Index:66
  • Related Information:Catalog(3989)
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  • Company Name:TargetMol Chemicals Inc.
  • Tel:021-021-33632979 15002134094
  • Products Intro:Product Name:GW1929
    CAS:196808-24-9
    Package:1 mL;10 mg;100 mg;25 mg;5 mg;50 mg Remarks: 90+%,具体纯度信息请见官网
  • CB Index:58
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  • Company Name:AdooQ Bioscience CHINA
  • Tel:025-58849295 18951903616;
  • Products Intro:Product Name:GW1929
    CAS:196808-24-9
    Purity:0.98 Package:1mg;5mg;10mg;25mg;50mg;100mg More...
  • CB Index:60
  • Related Information:Catalog(2990)
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