LY2940680

1258861-20-9 Basic information More

Product Name:LY2940680
Synonyms: Taladegib (LY2940680) 4-Fluoro-N-methyl-N-[1-[4-(1-methyl-1H-pyrazol-5-yl)-1-phthalazinyl]-4-piperidinyl]-2-(trifluoromethyl)benzamide LY 2940680 LY2940680 LY2940680 (Taladegib) Taladegib Taladegib hydrochloride 4-Fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluo 4-Fluoro-N-methyl-N-[1-[4-(1-methyl-1H-pyrazol-5-yl)-1-phthalazinyl]-4-piperidinyl]-2-(trifluoromethyl)benzamide
CAS:1258861-20-9
MF:C26H24F4N6O
MW:512.5
EINECS:
Mol File:1258861-20-9.mol

USE

Smoothened (Smo) is a GPCR-like receptor that, with Patched, mediates hedgehog (Hh) signaling to regulate gene expression through the Gli transcription factors. LY2940680 is an antitumor agent that binds to the human Smo receptor and inhibits Sonic Hh-induced Gli1 expression (IC50 = ~2.4 nM in vitro). The potential anticancer activity of LY2940680 is currently under clinical investigation.[Cayman Chemical]

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Company Name:Chembest Research Laboratories Limited
Tel:+86-21-20908456
Products Intro:Product Name:LY 2940680
CAS:1258861-20-9
Remarks:C13843 More...
CB Index:61
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Company Name:Dalian Meilun Biotech Co., Ltd.
Tel:0411-62910999 13889544652
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CAS:1258861-20-9
Purity:>98% Package:20MG Remarks:6800 More...
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Company Name:Shanghai Topbiochem Technology Co., Ltd
Tel:021-58170097
Products Intro:Product Name:LY2940680
CAS:1258861-20-9
Purity:98% Package:1g;10g;100g
CB Index:58
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