Foretinib (GSK1363089)
849217-64-7 Basic informationMore
- Product Name:Foretinib (GSK1363089)
- Synonyms: GSK 1363089 N-[3-Fluoro-4-[[6-(methyloxy)-7-[[3-(morpholin-4-yl)propyl]oxy]quinolin-4-yl]oxy]phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide N-[3-Fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide XL-880,Foretinib XL880(GSK1363089) FORETINIB GLAXOSMITHKLINE PAPILLARY RENAL CELL CARCINOMA PHASE IIRSCH. TRIANGLE PARK, NC (SEE ALSO HEAD/NECK) (888) 825-5249 foretinib N1-{3-fluoro-4-[(6-(Methyloxy)-7-{[3-(4-Morpholinyl)propyl]oxy}-4-quinolinyl)oxy]phenyl}-N1'-(4-fluorophenyl)-1,1-cyclopropanedicarboxaMide Foretinib (GSK1363089, XL880)
- CAS:849217-64-7
- MF:C34H34F2N4O6
- MW:632.65
- EINECS:
- Mol File:849217-64-7.mol
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USE
Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met and KDR with IC50 of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit, PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.
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- Foretinib (GSK1363089)
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- CAS:849217-64-7
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1Ton
- 2025-04-04
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CAS:849217-64-7
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- Products Intro:Product Name:N-[3-Fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
CAS:849217-64-7
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Purity:99% HPLC Package:50Mg,100Mg,500Mg,1g,5g,10g,50g,100g,500g,1kg Remarks:XYA0538 More... - CB Index:55
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