Basic information Supplier

LY 341495

Basic information Supplier
201943-63-7 Basic informationMore
USE
LY341495 is a potent and selective antagonist of the group II metabotropic glutamate receptors (mGluR), mGluR2 and mGluR3 (IC50s = 21 and 14 nM, respectively, for human isoforms). It less effectively blocks mGluR8 and mGluR7 (IC50s = 173 and 990 nM, respectively) and weakly antagonizes mGluR1, mGluR5, and mGluR4 (IC50s = 6.8, 8.2, and 22 μM, respectively). In rat forebrain tissue, LY341495 may bind mGluR3 more avidly than mGluR2. LY341495 can be effectively used in isolated cells, tissues, and in vivo. In mice, it penetrates the blood-brain barrier and has been used to study the roles of mGlu2/3 receptors in the brain.[Cayman Chemical]<p>LY 341495 is a potent and selective antagonist of the group II metabotropic glutamate receptors (mGluR), mGluR2 and mGluR3 (IC50s = 21 and 14 nM, respectively, for human isoforms). It less effectively blocks mGluR8 and mGluR7 (IC50s = 173 and 990 nM, respectively) and weakly antagonizes mGluR1, mGluR5, and mGluR4 (IC50s = 6.8, 8.2, and 22 μM, respectively). In rat forebrain tissue, LY341495 may bind mGluR3 more avidly than mGluR2. LY341495 can be effectively used in isolated cells, tissues, and in vivo. In mice, it penetrates the blood-brain barrier and has been used to study the roles of mGlu2/3 receptors in the brain.[Cayman Chemical]</p>

Browse by Nationality 201943-63-7 Suppliers >Global suppliers

Beijing (7) Shanghai (35) Tianjin (1) Chongqing (1) Sichuan (2) Guangdong (7) Zhejiang (2) Fujian (2) Hubei (2) Shandong (1) Henan (1) Anhui (2) Jiangsu (7) Jiangxi (1) Other (2) Member (72) All (73)
Please select the suppliers
Recommend You Select Member Companies
  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:821-50328103-801 18930552037
  • Products Intro:Product Name:LY 341495;(2S)-2-AMino-2-[(1S,2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl)propanoicacid
    CAS:201943-63-7
    Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More...
  • CB Index:69
  • Related Information:Catalog(15848)
  •  
  • Company Name:Chembest Research Laboratories Limited
  • Tel:021-20908456
  • Products Intro:Product Name:LY 341495
    CAS:201943-63-7
    Remarks:C14480 More...
  • CB Index:61
  • Related Information:Catalog(6008)
  •  
  • Company Name:TargetMol Chemicals Inc.
  • Tel:021-021-33632979 15002134094
  • Products Intro:Product Name:LY341495
    CAS:201943-63-7
    Package:1 mL;10 mg;100 mg;2 mg;25 mg;5 mg;50 mg Remarks: 90+%,具体纯度信息请见官网
  • CB Index:58
  • Related Information:Catalog(7854)
  •  
  • Company Name:ShangHai Caerulum Pharma Discovery Co., Ltd.
  • Tel: 18149758185
  • Products Intro:Product Name:LY-341495
    CAS:201943-63-7
    Purity:98% Package:1g;10g;100g
  • CB Index:58
  • Related Information:Catalog(3460)
  •  
  • Company Name:AdooQ Bioscience CHINA
  • Tel:025-58849295 18951903616;
  • Products Intro:Product Name:LY341495
    CAS:201943-63-7
    Purity:0.98 Package:1mg;5mg;10mg;25mg;50mg;100mg More...
  • CB Index:60
  • Related Information:Catalog(2989)
  •  
1 2 3 4 5 9