HET0016
339068-25-6 Basic informationMore
- Product Name:HET0016
- Synonyms: HET0016 N-HYDROXY-N'-(4-N-BUTYL-2-METHYLPHENYL)FORMANIDINE N-(4-BUTYL-2-METHYLPHENYL)-N'-HYDROXY-METHANIMIDAMIDE N-Hydroxy-N(4-butyl-2-methylphenyl)formamidine N-(4-butyl-2-methylphenyl)-N'-hydroxyiminoformamide N’-(4-Butyl-2-methylphenyl)-N-hydroxyformimidamide Methanimidamide, N'-(4-butyl-2-methylphenyl)-N-hydroxy- HET0016,HET-0016
- CAS:339068-25-6
- MF:C12H18N2O
- MW:206.28
- EINECS:
- Mol File:339068-25-6.mol
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USE
20-HETE is a major biologically active cytochrome P450 (CYP450) metabolite of arachidonic acid in the kidney and liver. It regulates renal vascular and tubular functions as well as vascular tone in the cerebral circulation. HET0016 is an inhibitor of 20-HETE formation in human renal microsomes with an IC50 of 8.9 nM, selectively inhibiting CYP4A and 4F isoforms. HET0016 inhibits CYP2C9, CYP2D6, and CYP3A4, enzymes important in drug metabolism, significantly less effectively with IC50s in the μM range. The IC50 values for inhibition of cyclooxygenase and epoxyeicosatrienoic acids (EETs) formation are 2.3 and 2.8 μM, respectively.[Cayman Chemical]
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- Company Name:J & K SCIENTIFIC LTD.
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- Products Intro:Product Name:N-Hydroxy-N'-(4-butyl-2-Methylphenyl)forMaMidine
CAS:339068-25-6
Package:100Mg,10Mg More... - CB Index:76
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- Company Name:Mashilabs (Shanghai) Co.,Ltd.
- Tel: 19916721580
- Products Intro:CAS:339068-25-6
Purity:0.98 - CB Index:58
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- Company Name:Shanghai EFE Biological Technology Co., Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:N-Hydroxy-N’-(4-butyl-2-methylphenyl)formamidine
CAS:339068-25-6
Purity:98% Package:1mg;5mg;10mg More... - CB Index:58
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- Company Name:Shenzhen Polymeri Biochemical Technology Co., Ltd.
- Tel:+86-400-002-6226 +86-13028896684;
- Products Intro:Product Name:N-Hydroxy-N'-(4-butyl-2-Methylphenyl)forMaMidine
CAS:339068-25-6
More... - CB Index:58
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- Company Name:Zhejiang J&C Biological Technology Co.,Limited
- Tel:+1-2135480471 +1-2135480471
- Products Intro:Product Name:N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine
CAS:339068-25-6
Purity:99% Package:5KG;1KG Remarks:N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine - CB Index:58
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