TIN PROTOPORPHYRIN IX DICHLORIDE
14325-05-4 Basic informationMore
- Product Name:TIN PROTOPORPHYRIN IX DICHLORIDE
- Synonyms: tin protoporphyrin IX TINPROTOPORPHYRIN Nsc267099 Stannate(2-) dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid] Tin Protoporphyrin IX (chloride) TIN PROTOPORPHYRIN IX DICHLORIDE SnPPIX Tin protoporphyrin I
- CAS:14325-05-4
- MF:C34H36Cl2N4O4Sn
- MW:754.29
- EINECS:
- Mol File:14325-05-4.mol
-
USE
<p>Heme oxygenase (HO) converts protoheme to biliverdin, which in turn is enzymatically metabolized to bilirubin . While HO-2 is constitutively expressed, HO-1 can be induced by its heme substrate as well as by heavy metals, oxidizing agents, and other environmental stresses. TIN PROTOPORPHYRIN IX DICHLORIDE(SnPPIX) is a synthetic heme analog that selectively inhibits HO-1 (Ki = 11 nM) over HO-2 (IC50 = 7.5 μM). It also weakly inhibits endothelial nitric oxide synthase and soluble guanylyl cyclase (IC50s = 35 and 30 nM, respectively). SnPPIX prevents hyperbilirubinemia in neonates by blocking HO-1 activity that increases postnatally. It is rapidly cleared from plasma and persists in certain tissues, including kidney, liver, and spleen. SnPPIX is commonly used as a tool to study the role of HO-1 activity in cells and in animals.[Cayman Chemical]</p>
Browse by Nationality 14325-05-4 Suppliers >Global suppliers
Beijing (2) Shanghai (16) Tianjin (2) Chongqing (1) Sichuan (2) Hubei (2) Henan (2) Jiangsu (2) Hong Kong (1) Other (1) Member (31) All (31)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Sn(IV) Protoporphyrin IX dichloride
CAS:14325-05-4
Package:1g,250Mg More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:Tin protoporphyrin IX dichloride
CAS:14325-05-4
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
- Related Information:Catalog(15839)
- Company Name:ShangHai Caerulum Pharma Discovery Co., Ltd.
- Tel:18149758185 18149758185
- Products Intro:Product Name:Tin Protoporphyrin IX dichloride (NSC 267099; SnPPIX )
CAS:14325-05-4
Purity:98% Package:1g;10g;100g - CB Index:58
- Related Information:Catalog(3466)
- Company Name:Chengdu Aslee Biopharmaceuticals, Inc
- Tel:028-85305008 02885305008
- Products Intro:Product Name:Sn(IV) Protoporphyrin IX dichloride
CAS:14325-05-4
Purity:95% HPLC Package:1G, 5G,10G, 25G, 50G, 100G, 250G, 500G More... - CB Index:50
- Related Information:Catalog(1006)
- Company Name:ShangHai Angti Biotechnology Co., Ltd.
- Tel: 13764913901
- Products Intro:Product Name:TIN PROTOPORPHYRIN IX DICHLORIDE
CAS:14325-05-4
- CB Index:55
- Related Information:Catalog(5007)
- Company Name:Shanghai EFE Biological Technology Co., Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:Tin protoporphyrin IX dichloride
CAS:14325-05-4
Purity:95% Package:5mg;10mg;25mg More... - CB Index:58
- Related Information:Catalog(9806)
- Company Name:Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel: 15076683720
- Products Intro:Product Name:Tin protoporphyrin IX dichloride
CAS:14325-05-4
Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only. - CB Index:55
- Related Information:Catalog(4597)
- Company Name:Aikon International Limited
- Tel:025-58851090 13611564524
- Products Intro:Product Name:TIn protoporphyrin ix dichloride
CAS:14325-05-4
Purity:95+% Package:1g;5g;10g - CB Index:58
- Related Information:Catalog(15951)