TIN PROTOPORPHYRIN IX DICHLORIDE
14325-05-4 Basic informationMore
- Product Name:TIN PROTOPORPHYRIN IX DICHLORIDE
- Synonyms: tin protoporphyrin IX TINPROTOPORPHYRIN Nsc267099 Stannate(2-) dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid] Tin Protoporphyrin IX (chloride) TIN PROTOPORPHYRIN IX DICHLORIDE SnPPIX Tin protoporphyrin I
- CAS:14325-05-4
- MF:C34H36Cl2N4O4Sn
- MW:754.29
- EINECS:
- Mol File:14325-05-4.mol
-
USE
<p>Heme oxygenase (HO) converts protoheme to biliverdin, which in turn is enzymatically metabolized to bilirubin . While HO-2 is constitutively expressed, HO-1 can be induced by its heme substrate as well as by heavy metals, oxidizing agents, and other environmental stresses. TIN PROTOPORPHYRIN IX DICHLORIDE(SnPPIX) is a synthetic heme analog that selectively inhibits HO-1 (Ki = 11 nM) over HO-2 (IC50 = 7.5 μM). It also weakly inhibits endothelial nitric oxide synthase and soluble guanylyl cyclase (IC50s = 35 and 30 nM, respectively). SnPPIX prevents hyperbilirubinemia in neonates by blocking HO-1 activity that increases postnatally. It is rapidly cleared from plasma and persists in certain tissues, including kidney, liver, and spleen. SnPPIX is commonly used as a tool to study the role of HO-1 activity in cells and in animals.[Cayman Chemical]</p>
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:18210857532 18210857532
- Products Intro:Product Name:Sn(IV) Protoporphyrin IX dichloride
CAS:14325-05-4
Package:1g,250Mg More... - CB Index:76
- Related Information:Catalog(94588)
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel: 18930552037
- Products Intro:Product Name:Tin protoporphyrin IX dichloride
CAS:14325-05-4
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
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- Company Name:ShangHai Caerulum Pharma Discovery Co., Ltd.
- Tel:18149758185 18149758185
- Products Intro:Product Name:Tin Protoporphyrin IX dichloride (NSC 267099; SnPPIX )
CAS:14325-05-4
Purity:98% Package:1g;10g;100g - CB Index:58
- Related Information:Catalog(3493)
- Company Name:Bide Pharmatech Ltd.
- Tel:400-164-7117 18317119277
- Products Intro:Product Name:TIn protoporphyrin ix dichloride
CAS:14325-05-4
Purity:95% Package:50mg;100mg;250mg;1g Remarks:BD00944228 - CB Index:60
- Related Information:Catalog(40000)
- Company Name:Chengdu Aslee Biopharmaceuticals, Inc
- Tel:028-85305008 02885305008
- Products Intro:Product Name:Sn(IV) Protoporphyrin IX dichloride
CAS:14325-05-4
Purity:95% HPLC Package:1G, 5G,10G, 25G, 50G, 100G, 250G, 500G More... - CB Index:50
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- Company Name:ShangHai Angti Biotechnology Co., Ltd.
- Tel: 13764913901
- Products Intro:Product Name:TIN PROTOPORPHYRIN IX DICHLORIDE
CAS:14325-05-4
- CB Index:55
- Related Information:Catalog(4973)
- Company Name:Shanghai Haozhixiang Biotechnology Co., Ltd
- Tel:526763801 13301653310
- Products Intro:Product Name:TIN PROTOPORPHYRIN IX DICHLORIDE
CAS:14325-05-4
Purity:98% - CB Index:55
- Related Information:Catalog(7997)
- Company Name:Shanghai EFE Biological Technology Co., Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:Tin protoporphyrin IX dichloride
CAS:14325-05-4
Purity:95% Package:5mg;10mg;25mg More... - CB Index:58
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