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Olopatadine hydrochloride

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<p>Olopatadine hydrochloride is a potent, selective antagonist of the H1 histamine receptor (Ki = 16-41.1 nM), with much lower affinities for the H2 and H3 receptors (Ki = 43.4 and 172 μM, respectively). It blocks histamine-induced phosphoinositide turnover in isolated cells (IC50 = 9.5-39.9 nM) and prevents passive cutaneous anaphylaxis in rats (ED50 = 49 μg/kg) and anaphylactic bronchoconstriction in guinea pigs (ID50 = 30 μg/kg). Olopatadine is effective in treating allergic rhinitis and conjunctivitis. It also suppresses itch in patients with well-controlled chronic urticaria. In humans, this antihistamine does not cause cognitive or psychomotor impairment at therapeutic doses.[Cayman Chemical]</p>
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  • Company Name:Qingdao Kingway Pharmtech Co.,Ltd.
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  • Products Intro:Product Name:Olopatadine Hydrochloride
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    Purity:99% HPLC Package:按需包装
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  • Company Name:Shandong Mingfeng Pharmaceutical and Technology Co. Ltd
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    CAS:140462-76-6
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  • Company Name:Beijing Lianben Pharm-Chemicals Tech. Co.,Ltd
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  • Products Intro:Product Name:Olopatadine Hydrochloride
    CAS:140462-76-6
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  • Products Intro:Product Name:Olopatadine hydrochloride, 99%, a selective H1 receptor antagonist
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    Purity:>98% Package:100g;500g;1kg Remarks:C13957 More...
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