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140462-76-6

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<p>Olopatadine hydrochloride is a potent, selective antagonist of the H1 histamine receptor (Ki = 16-41.1 nM), with much lower affinities for the H2 and H3 receptors (Ki = 43.4 and 172 μM, respectively). It blocks histamine-induced phosphoinositide turnover in isolated cells (IC50 = 9.5-39.9 nM) and prevents passive cutaneous anaphylaxis in rats (ED50 = 49 μg/kg) and anaphylactic bronchoconstriction in guinea pigs (ID50 = 30 μg/kg). Olopatadine is effective in treating allergic rhinitis and conjunctivitis. It also suppresses itch in patients with well-controlled chronic urticaria. In humans, this antihistamine does not cause cognitive or psychomotor impairment at therapeutic doses.[Cayman Chemical]</p>
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  • Company Name:Hebei Corol Fine Chemical CO.,LTD
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  • Products Intro:Product Name:Olopatadine Hydrochloride
    CAS:140462-76-6
    Purity:98.5%HPLC Package:15000RMB/1KG More...
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  • Company Name:Xuzhou Fred Chemical Technology Co., Ltd.
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  • Company Name:CGeneTech (Suzhou, China) Co., Ltd.
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  • Products Intro:Product Name:Olopatadine HCl
    CAS:140462-76-6
    Purity:99% HPLC% Package:100g,1kg,10kg 25kg More...
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  • Company Name:Cangzhou Weizhidamei Pharmaceutical Co., Ltd.
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  • Company Name:Chongqing Kangzhou Zhitong Pharmaceutical Technology Co., Ltd.
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  • Products Intro:Product Name:Olopatadine hydrochloride
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    Purity:99% Package:1kg:5kg:10kg:44kg
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  • Company Name:Tianjin Keluo Pharmaceutical Technology Co. LTD
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  • Products Intro:Product Name:Olopatadine hydrochloride
    CAS:140462-76-6
    Purity:99% HPLC Package:1KG;500克;200克;100克
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  • Company Name:J & K SCIENTIFIC LTD.
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  • Products Intro:Product Name:Olopatadine hydrochloride, 99%, a selective H1 receptor antagonist
    CAS:140462-76-6
    Purity:99% Package:10MG;50MG More...
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