ascochlorin
26166-39-2 Basic informationMore
- Product Name:ascochlorin
- Synonyms: 3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,4E)-3-methyl-5-[(1R)-1β,2β,6β-trimethyl-3-oxocyclohexyl]-2,4-pentadienyl]benzaldehyde Ilicicolin D 3-Chloro-4,6-dihydroxy-2-methyl-5-(3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)-2,4-pentadienyl)benzaldehyde (1R-(1alpha(2E,4E),2beta,6beta))- Antibiotic ll-Z1272 gamma ascochlorin Benzaldehyde, 3-chloro-4,6-dihydroxy-2-methyl-5-(3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)-2,4-pentadienyl)-, (1R-(1alpha(2E,4E),2beta,6beta))- beta-Resorcylaldehyde, 5-chloro-6-methyl-3-(3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)-2,4-pentadienyl)-, (E,E)- Ll-Z 1272 gamma
- CAS:26166-39-2
- MF:C23H29ClO4
- MW:404.931
- EINECS:
- Mol File:26166-39-2.mol
-
USE
Ascochlorin is an isoprenoid antibiotic and antiviral that has diverse effects on mammalian cells. It suppresses PMA-induced invasion in renal carcinoma cells (IC50 = ~10 μM) by inhibiting the expression of matrix metalloproteinase-9. At 2 μM, ascochlorin profoundly increases the expression of p53 by increasing protein stability in cancer cells, and, at 50 μm, it inhibits signaling through STAT3. Ascochlorin also binds and inhibits the mitochondrial cytochrome bc1 complex, blocking reduction of cytochrome b by ubiquinone.[Cayman Chemical]
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- Company Name:Shanghai EFE Biological Technology Co., Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:Ascochlorin
CAS:26166-39-2
Purity:98% Package:500μg;2.5mg More... - CB Index:58
- Related Information:Catalog(9806)
- Company Name:Beijing Jin Ming Biotechnology Co., Ltd.
- Tel:010-60605840 18892239720
- Products Intro:Product Name:Ascochlorin
CAS:26166-39-2
Package:500UG - CB Index:58
- Related Information:Catalog(12308)
- Company Name:Lynnchem
- Tel:86-(0)29-85992781 17792393971
- Products Intro:Product Name:ascochlorin
CAS:26166-39-2
Purity:>98% by HPLC Package:0.5mg;2.5mg More... - CB Index:58
- Related Information:Catalog(4587)
- Company Name:Shenzhen Polymeri Biochemical Technology Co., Ltd.
- Tel:+86-400-002-6226
- Products Intro:Product Name:Ascochlorin
CAS:26166-39-2
More... - CB Index:58
- Related Information:Catalog(56086)
- Company Name:Zhejiang Huida Biotech Co., LTD
- Tel:0571-89903882 13626641628
- Products Intro:Product Name:Ascochlorin
CAS:26166-39-2
Purity:99% HPLC Package:10mg；100mg；1g；10g；100g - CB Index:58
- Related Information:Catalog(3656)
- Company Name:Energy Chemical
- Tel:021-58432009 400-005-6266
- Products Intro:Product Name:Ascochlorin
CAS:26166-39-2
Purity:NULL Package:1000g;500g;500ug Remarks:NULL - CB Index:58
- Related Information:Catalog(44843)