(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxooct-1-enyl]cyclopentyl]hept-5-enoic acid
191919-01-4 Basic informationMore
- Product Name:(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxooct-1-enyl]cyclopentyl]hept-5-enoic acid
- Synonyms: (Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxooct-1-enyl]cyclopentyl]hept-5-enoic acid 8-iso-15-keto-PGF2alpha LOLJEILMPWPILA-RLXHZABYSA-N 8-iso-15-keto Prostaglandin F2α Prosta-5,13-dien-1-oic acid, 9,11-dihydroxy-15-oxo-, (5Z,8β,9α,11α,13E)-
- CAS:191919-01-4
- MF:C20H32O5
- MW:352.47
- EINECS:
- Mol File:191919-01-4.mol
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USE
8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2α) is a prostaglandin-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-iso PGF2α is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-iso PGF2α is infused into rabbits. Early in the infusion (within 1-2 minutes) 8-iso -15-keto PGF2α was a major component of the metabolite profile, which was comprised mostly of unmetabolized 8-iso PGF2α. 8-iso -15-keto PGF2α is a vasoconstrictor when tested on the rat isolated thoracic aorta, acting via the TP (thromboxane) receptor.[Cayman Chemical]
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- Products Intro:Product Name:8-iso-15-keto Prostaglandin F2α
CAS:191919-01-4
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g - CB Index:58
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CAS:191919-01-4
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CAS:191919-01-4
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- Products Intro:Product Name:8-iso-15-keto Prostaglandin F2α
CAS:191919-01-4
Purity:95% - CB Index:58
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