Losartan Carboxaldehyde
114798-36-6 Basic informationMore
- Product Name:Losartan Carboxaldehyde
- Synonyms: 2-Butyl-4-chloro-1-[[2(1H-tetrazol-5-yl)[1,1biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde DUP 167 EXP 3179 Losartan Carboxaldehyde Discontinued see product # L470505 Losartan Carboxaldehyde 2-(Butyl-d3)-4-chloro-1-[[2(1H-tetrazol-5-yl)[1,1biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde Losartan Carboxaldehyde-d3 Losartan EP IMpurity K (LosaratnCarboxaldehyde)
- CAS:114798-36-6
- MF:C22H21ClN6O
- MW:420.89
- EINECS:
- Mol File:114798-36-6.mol
-
USE
Losartan carboxaldehyde is an intermediate aldehyde metabolite of the angiotensin II type 1 receptor antagonist, losartan . It does not block angiotensin receptors, but instead inhibits endothelial cyclooxygenase (COX)-2 expression, thereby exerting anti-inflammatory actions. At 1 μM in vitro, losartan carboxaldehyde has also been shown to block the upregulation of intercellular adhesion molecule (ICAM)-1 mRNA and COX-dependent generation of thromboxane A2 and prostaglandin F2α . Losartan carboxaldehyde can also act as a partial agonist (EC50 = 17.1 μM) of the insulin-sensitizing peroxisome proliferator-activated receptor γ in vitro.[Cayman Chemical]
Lastest Price from Losartan Carboxaldehyde manufacturers
- Allisartan Isoproxil Impurity 14
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- US $0.00 /mg
- CAS:114798-36-6
- Min. Order: 10mg
- Purity: 0.98
- Supply Ability: 10g
- 2025-02-06
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Losartan Carboxaldehyde
CAS:114798-36-6
Package:100Mg,10Mg More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
- Tel:025-66099280 17798518460
- Products Intro:Product Name:Losartan Carboxaldehyde_x000b_Discontinued see product # L470505
CAS:114798-36-6
Purity:95% Package:1g;5g;10g More... - CB Index:55
- Related Information:Catalog(19915)
- Company Name:ChemStrong Scientific Co.,Ltd
- Tel:0755-0755-66853366 13670046396
- Products Intro:Product Name:Losartan EP Impurity K
CAS:114798-36-6
Purity:95% HPLC Package:10mg;25mg;50mg More... - CB Index:56
- Related Information:Catalog(18097)
- Company Name:Nanjing XiZe Biotechnology CO., Ltd.
- Tel:025-66023220 0086-15250997978
- Products Intro:Product Name:Losartan EP Impurity K
CAS:114798-36-6
Purity:95% HPLC Package:10mg;25mg;50mg;100mg;250mg;500mg;1g - CB Index:55
- Related Information:Catalog(7892)
- Company Name:Beijing Solarbio Science & Tecnology Co., Ltd.
- Tel:010-50973186 4009686088
- Products Intro:CAS:114798-36-6
Package:20mg More... - CB Index:68
- Related Information:Catalog(18338)