MDL-12,330A HCl is the hydrochloride salt preparation of MDL-12,330A, an inhibitor of A cyclase, PDE (cyclic AMP (cAMP) and cyclic GMP (cGMP) phosphodiesterases). MDL-12,330A is described to block K+-stimulated and histamine-stimulated cAMP formation. Inhibition of cAMP activity by MDL-12,330A has been employed to identify cAMP-mediated activity in myocardial inotropic functioning and in the regulation of nicotinic cholinergic synapses.
