Potassium 4-tert-butylphenyltrifluoroborate is a trifluoroborate building-block compound that may be employed in a variety of transformations. The trifluoroborate compounds have been demonstrated to behave as boronic acid surrogates with greater stability and diminished sensitivity to water over the corresponding boronic acids. Potassium 4-tert-butylphenyltrifluoroborate may be employed in cross-coupling protocols as well as in organometallic-catalyzed asymmetric conjugate additions.