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X-376
X-376
$32 - $1881
Product name
X-376
Cas No
1365267-27-1
MF
C25H25Cl2FN6O3
MW
547.41
MDL Number
MFCD25976868
Synonyms
X-376;X-396;6-Amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-3-pyridazinecarboxamide;Ensartinib;(R)-6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-N-(4-(4-methylpiperazine-1-carbonyl)phenyl)pyridazine-3-carboxamide;6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-(4-methylpiperazine-1-carbonyl)phenyl]pyridazine-3-carboxamide;CS-1720;3-Pyridazinecarboxamide, 6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-
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Cayman Chemical
Arctom
AK Scientific
ChemScene
DC Chemicals
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10mm*1mlindmso(solution)
50mg
100mg
250mg
1g
10mm*1mlindmso(solid+solvent)
1mg
2mg
5mg
10mg
25mg
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Brand
Packaging
Price
Product name
AK Scientific
2125DN
1mg
$133
CID56960447
AK Scientific
2125DN
5mg
$252
CID56960447
Arctom
HY-16590R
5mg
$262
X-376 (Standard)
Arctom
SLK-S6505
2mg
$140
X-376
Arctom
HY-16590
10mg
$143
X-376
Arctom
HY-16590
2mg
$53
X-376
Arctom
HY-16590
5mg
$105
X-376
Arctom
HY-16590
10mM*1mLinDMSO(Solid+Solvent)
$119
X-376
Arctom
HY-16590
10mM*1mLinDMSO(Solution)
$126
X-376
Arctom
SLK-S6505
5mg
$283
X-376
1
of
4
Properties
Boiling point
695.1±55.0 °C(Predicted)
Density
1.428±0.06 g/cm3(Predicted)
storage temp.
Store at -20°C
solubility
Ethanol:13.0(Max Conc. mg/mL);23.75(Max Conc. mM)
form
A crystalline solid
pka
10.70±0.70(Predicted)
color
White to off-white
InChIKey
ONPGOSVDVDPBCY-CQSZACIVSA-N
SMILES
C1(C(NC2=CC=C(C(N3CCN(C)CC3)=O)C=C2)=O)=NN=C(N)C(O[C@@H](C2=C(Cl)C=CC(F)=C2Cl)C)=C1
Safety Information
Symbol(GHS)
Signal word
Warning
Hazard statements
H302:
Harmful if swallowed
Precautionary statements
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Description
X-376 is an ALK inhibitor with potential efficacy in the treatment of non-small cell lung cancer.
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Suppliers and manufacturers
TargetMol Chemicals Inc.
$89.00
/5mg
X-376
CAS:1365267-27-1
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InvivoChem
Nantong HI-FUTURE Biology Co., Ltd.
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