TC-N 1752;AcetaMide, N-[2-Methyl-3-[[4-[4-[[4-(trifluoroMethoxy)phenyl]Methoxy]-1-piperidinyl]-1,3,5-triazin-2-yl]aMino]phenyl]-;Nav1.7 blocker 52;TC-N 1752-d5;N-[2-METHYL-3-[[4-[4-[[4-(TRIFLUOROMETHOXY)PHENYL]METHOXY]-1-PIPERIDINYL]-1,3,5-TRIAZIN-2-YL]AMINO]PHENYL]ACETAMIDE;TCN 1752,TC N 1752;TC-N 1752, 10 mM in DMSO
Soluble to 100 mM in DMSO and to 10 mM in 1eq. HCl
form
Powder
pka
14.80±0.70(Predicted)
color
White to off-white
Description
TC-N 1752 is a potent, state-dependent inhibitor of Nav1.7, which is a neuronal voltage gated sodium channel and a critical mediator of pain sensitization.