Robenidine hydrochloride possesses a weak solubility in water (<1 mg/L), but is soluble in organic solvents: 94 mg/L in dimethylsulfoxide, 46 mg/L in dimethylformamide, 20 mg/L in pyridine and 6.3 mg/L in ethanol (95%). The Log Kow is 3.3 (EFSA, 2004a).