≥27.2 mg/mL in DMSO; insoluble in H2O; ≥24.75 mg/mL in EtOH
form
solid
color
Off-white to yellow
Description
Ro3280 is a Polo-like kinase 1 (PLK1) inhibitor. Ro3280 shows strong antitumor activity in xenograft mouse models, has good selectivity against other kinases and has excellent in vitro cellular potency.
