Olodaterol

$56 - $1700

Product nameOlodaterol
Cas No868049-49-4
MFC21H26N2O5
MW386.44
EINECS813-858-3
MDL NumberMFCD16619349

Synonyms

6-Hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one;2H-1,4-Benzoxazin-3(4H)-one, 6-hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-;BI 1744(Olodaterol;Striverdi Respimat);Olodaterol;Olodaterol ImpurityＡ　;BI-1744;Striverdi

show less show more

Price

14 prices

Brand less more

Cayman Chemical Chemenu AK Scientific American Custom Chemicals Corporation Biosynth Carbosynth DC Chemicals
Package less more

1mg 2mg 5mg 10mg 25mg 100mg 250mg 1g

Clear All Done

Brand	Packaging	Price	Product name
AK Scientific 4736BB	2mg	$171	Olodaterol
American Custom Chemicals Corporation API0014046	5MG	$501.28	OLODATEROL
Biosynth Carbosynth FH152793	10mg	$250	Olodaterol
Biosynth Carbosynth FH152793	25mg	$325	Olodaterol
Biosynth Carbosynth FH152793	1mg	$56	Olodaterol
Biosynth Carbosynth FH152793	2mg	$90	Olodaterol
Biosynth Carbosynth FH152793	5mg	$160	Olodaterol
Cayman Chemical 21794	1mg	$89	Olodaterol
Cayman Chemical 21794	10mg	$490	Olodaterol
Cayman Chemical 21794	5mg	$289	Olodaterol

1of2

Properties

Boiling point	649.0±55.0 °C(Predicted)
Density	1.250
solubility	DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml
form	A crystalline solid
pka	9.42±0.20(Predicted)
Stability	Hygroscopic

Safety Information

Symbol(GHS)

Signal word

Danger

Hazard statements

H302：Harmful if swallowed

H319：Causes serious eye irritation

H372：Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P260：Do not breathe dust/fume/gas/mist/vapours/spray.

P264：Wash hands thoroughly after handling.

P264：Wash skin thouroughly after handling.

P270：Do not eat, drink or smoke when using this product.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312：IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338：IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314：Get medical advice/attention if you feel unwell.

P330：Rinse mouth.

P501：Dispose of contents/container to..…

Description

In 2013, olodaterol (also known BI-1744 CL) was approved for the treatment of chronic obstructive pulmonary disease (COPD) in Russia (March), Canada (June), and the EuropeanUnion (October). Olodaterol is delivered via the Respimat? Soft Mist? inhaler. Olodaterol was discovered from an effort to identify a β2-adrenergic receptor agonist that could be given once daily and with a superior safety profile over known β2- adrenergic receptor agonists. Olodaterol is a potent β2 agonist (EC₅₀=0.1 nM, intrinsic activity=88%) and is highly selective for the β2 receptor over β1 and β3 receptors. In preclinical models in guinea pigs and dogs, olodaterol had a rapid onset of action and provided bronchoprotection over 24 h. Mechanistic studies indicated that olodaterol forms a highly stable complex with the β2-adrenergic receptor, with a dissociation half-life of 17.8 h. The synthesis of olodaterol proceeds through an (R)-styrene epoxide that is prepared via enantioselective reduction of an α-chloroketone intermediate. Ring opening of the epoxide with 1-(4- methoxyphenyl)-2-methylpropan-2-amine provides olodaterol.

Related product price

1H-BenziMidazole-7-carboxylic acid, 1-[[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]Methyl] -2-ethoxy-, ethyl ester $60-970 O-Desethyl Azilsartan $460-1455 Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate $9-2194.5

Suppliers and manufacturers

Hebei Yanxi Chemical Co., Ltd.

$50.00/1KG

olodaterol

CAS:868049-49-4
career henan chemical co

$1.00/1KG

6-Hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one

CAS:868049-49-4
Shanghai Daken Advanced Materials Co.,Ltd
ATK CHEMICAL COMPANY LIMITED
Anhui Dexinjia Biopharm Co., Ltd
BOC Sciences
Chongqing Chemdad Co., Ltd
Fuxin Pharmaceutical
Neostar United (Changzhou) Industrial Co., Ltd.
Hebei Miaobian Biotechnology Co., Ltd

More related product prices

1H-BenziMidazole-7-carboxylic acid, 1-[[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]Methyl] -2-ethoxy-, ethyl ester
O-Desethyl Azilsartan
Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate

Send Inquriy