MIXED GANGLIOSIDES

Gangliosides are acidic membrane sphingolipids that contain sialic acid and oligosaccharide moieties. They have roles in cell proliferation, differentiation, adhesion, neuronal plasticity, intra- and intercellular signaling, and neurogenesis. They accumulate in a variety of lysosomal storage disorders including Sandhoff, Tay-Sachs, and Niemann-pick diseases. Ganglioside Mixture contains the gangliosides asialo G_M1, G_M1, G_D1a, G_D1B, and G_T1b and is intended for use as a reference standard for the detection of these gangliosides in various samples by TLC, LC-, or GC-MS. [Matreya, LLC. Catalog No. 1511]