Indinavir

$104 - $4725

Product nameIndinavir
Cas No150378-17-9
MFC36H47N5O4
MW613.79
MDL NumberMFCD00866938

Synonyms

INDINAVIR;Indinavir&Int.;(1(1S,2R)5(S))-2,3,5-TRIDEOXY-N-(2,3-DIHYDRO-2HYDROXY-1H-INDEN-1-YI)-;(1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-pentonamide;[I(1S，2R)，5(S)]-2，3，5-Trideoxy-N-(2，3．Dihydro-2-hydrox-Lh-inden-1-y1)-5-[2-[[(1，1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide;L-735524;MK-639：Cfixivan;Indinavir(MK-639

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Price

27 prices

Brand less more

AHH CSNpharm Arctom ACHEMBLOCK AvaChem TRC Usbiological Matrix Scientific AK Scientific Medical Isotopes, Inc. American Custom Chemicals Corporation DC Chemicals
Package less more

0.01g 50mg 100mg 1g 1.00g 10mm*1mlindmso(solution) 1mg 10mg 25mg 5mg 10mm*1mlindmso(solid+solvent)

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Brand	Packaging	Price	Product name
ACHEMBLOCK R16024	25MG	$215	Indinavir
ACHEMBLOCK R16024	50MG	$365	Indinavir
AHH API-1193	0.01g	$565	Indinavir
AHH API-1193	0.01g	$565	Indinavir
AHH API-1193	0.01g	$565	Indinavir
AK Scientific E104	100mg	$786	Indinavir
AK Scientific E104	25mg	$262.48	Indinavir
American Custom Chemicals Corporation API0002994	10MG	$1252.78	INDINAVIR
American Custom Chemicals Corporation API0002994	1MG	$675.51	INDINAVIR
Arctom HY-B0689	10mM*1mLinDMSO(Solution)	$253	Indinavir

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Properties

Melting point	153-154°; mp 167.5-168°
alpha	D22 +24.1° (c = 0.0133 in chloroform)
Boiling point	877.9±65.0 °C(Predicted)
Density	1.25±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
form	Solid
pka	pKa 3.8/6.2(H2O,t undefined,Iundefined) (Uncertain)
color	White to off-white
Water Solubility	70mg/L(temperature not stated)

Safety Information

Symbol(GHS)

Signal word

Warning

Hazard statements

H302：Harmful if swallowed

H315：Causes skin irritation

H319：Causes serious eye irritation

H335：May cause respiratory irritation

Precautionary statements

P261：Avoid breathing dust/fume/gas/mist/vapours/spray.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312：IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352：IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338：IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Crixivan was launched in Australia, Switzerland, the UK and the US as an orally-bioavailable HIV-1 protease inhibitor. The compound can be prepared by coupling an optically active piperazine derivative with an epoxide derivative (now commercially available). The synthesis of the proteins, reverse transcriptase, integrase, structural proteins and a protease, required by the virus to complete its lifecycle, can be interupted if the protease enzyme is not capable of cleaving a proform polypeptide chain into these components. lndinavir inhibits this process and is more potent than the first approved protease inhibitor saquinavir. This effect was noted by the increase in CD4⁺ cells and a decrease in HIV RNA levels. Since indinavir is metabolized by the CYP3A4 isozyme, care must be taken with patients with hepatic insufficiency and to sex-related differences in the level of this enzyme. Other than nephrolithiasis (5%), indinavir is relatively safe and well tolerated.

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Suppliers and manufacturers

career henan chemical co

$3.00/3KG

Indinavir

CAS:150378-17-9
Dideu Industries Group Limited

$1.10/1g

Indinavir USP/EP/BP

CAS:150378-17-9
Biochempartner
CONIER CHEM AND PHARMA LIMITED
Baoji Guokang Healthchem Co., Ltd.
Baoji Guokang Healthchem co.,ltd
Hefei Hirisun Pharmatech Co., Ltd
Nextpeptide Inc
InvivoChem
Hefei TNJ Chemical Industry Co.,Ltd.

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