Heat shock protein 40 (Hsp40) is an Hsp70 co-chaperone protein that regulates the ATP-dependent binding of Hsp70 (Item Nos. 23002 | 22739) to target proteins.1 There are 44 members of the Hsp40 family in humans, and each Hsp40 contains a unique polypeptide-binding domain that binds and delivers specific target proteins to Hsp70. Hsp40 also contains a conserved HPD tripeptide that is critical to its role in driving conversion of Hsp70 from its ATP-bound form to its ADP-bound form to facilitate target loading.WARNING This product is not for human or veterinary use.
