Fosaprepitant dimeglumine

$5 - $4990

Product nameFosaprepitant dimeglumine
Cas No265121-04-8
MFC30H39F7N5O11P
MW809.63
EINECS682-419-4
MDL NumberMFCD23102059

Synonyms

Phosphonic acid, (3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:2);Unii-D35fm8T64x;[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(MethylaMino)-D-glucitol;1-Deoxy-1-(MethylaMino)-D-glucitol [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate;1-DEOXY-1-(METHYLAMINO)-D-GLUCITOL [[(2R,3S]-2-[(1R)-1-[3,5-BIS (TRIFLUOROMETHYL)PHENYL] PHENYL]ETHOXY]-(4-FLUOROPHENYL);3-[2(R)-[1(R)-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)Morpholin-4-ylMethyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-phosphinic acid bis(N-Methyl-D-glucaMine) salt;Fosaprepitant diMegluMine salt;Fosaprepitant dimeglumine, >=99%

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Price

45 prices

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Sigma-Aldrich Cayman Chemical CSNpharm Arctom Chemenu Crysdot TRC Biorbyt Ltd ApexBio Technology AK Scientific Medical Isotopes, Inc. ChemScene Biosynth Carbosynth Ambeed Chemtos DC Chemicals
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1mg 5mg 10mg 25mg 50mg 100mg 250mg 500mg 1g 2g 5g

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Brand	Packaging	Price	Product name
AK Scientific J11396	10mg	$226	Fosaprepitantdimeglumine
Ambeed A455841	1g	$126	Fosaprepitantdimeglumine
Ambeed A455841	5g	$423	Fosaprepitantdimeglumine
Ambeed A455841	5mg	$6	Fosaprepitantdimeglumine
Ambeed A455841	10mg	$8	Fosaprepitantdimeglumine
Ambeed A455841	50mg	$19	Fosaprepitantdimeglumine
Ambeed A455841	100mg	$28	Fosaprepitantdimeglumine
Ambeed A455841	250mg	$47	Fosaprepitantdimeglumine
ApexBio Technology B2145	50mg	$485	Fosaprepitantdimegluminesalt
Arctom AS564407	1g	$91	Fosaprepitantdimeglumine

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Properties

storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	≥50.24 mg/mL in DMSO; insoluble in EtOH; ≥13.16 mg/mL in H2O with ultrasonic
form	Powder
pka	Fosaprepitant dimeglumine has four functional groups which have pKa values of 3.05 ± 0.03, 4.92 ± 0.02, 9.67 ± 0.01 and 10.59 ± 0.03. The pka value of 3.05 corresponds to the morpholinium group, the pka of 4.92 corresponds to the monophosphonate group, the pka of 9.67 corresponds to the meglumine counter ion, and the pka of 10.59 corresponds to the triazolinone NH group.

Safety Information

Symbol(GHS)

Signal word

Warning

Hazard statements

H315：Causes skin irritation

H319：Causes serious eye irritation

Precautionary statements

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352：IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338：IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313：IF SKIN irritation occurs: Get medical advice/attention.

P337+P313：IF eye irritation persists: Get medical advice/attention.

Description

Fosaprepitant dimeglumine is a water-soluble prodrug form of the neurokinin-1 receptor antagonist aprepitant. Formulations containing fosaprepitant dimeglumine have been used to prevent chemotherapy-induced nausea and vomiting.

Related product price

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Suppliers and manufacturers

Hebei baicao biology science and technology co., ltd

$11.00/1kg

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$10.00/100kg

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Changzhou Rokechem Technology Co., Ltd.

$0.00/1Kg

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career henan chemical co

$7.00/1kg

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Shanghai Daken Advanced Materials Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Lianyungang happen teng technology co., LTD

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