Leptin is a 16 kDa protein hormone encoded by the obese (ob) gene with important effects in metabolism and regulating body weight. Leptin has dual actions, decreasing appetite and increasing energy consumption. Mutations in the ob gene or leptin receptor gene causes hyperphagia, reduced energy expenditure, and severe obesity. Studies have also shown that leptin is a regulator of reproductive function, bone metabolism and plays a significant role as an immunomodulator. This Enzyme Immunometric Assay (EIA) is based on a double-antibody sandwich technique specific for mouse and rat leptin. [Bertin Catalog No. A05176]WARNING This product is not for human or veterinary use.
