Recombinant murine IL-2 is produced in
E. coli and exhibits the following:
- Supports the growth of murine CTLL cells (murine T cell line), but not that of human T-cells.
- Strongly inhibits the binding of recombinant human IL-2 to murine responder cells.
- Weakly inhibits the binding to human responder cells.
- Shares identical biological and immunological activities with human IL-2.
- Is a convenient tool for extensive studies of the pharmacological and physiological activities of IL-2 in murine models.
- used for the stimulation of murine T-cells
