The human BLT1 receptor is a G protein-coupled receptor that mediates the proinflammatory effects of leukotriene B4 (LTB4).1 Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus.1 Sheep lung membranes have also been identified as a rich source for receptor isolation and purification.2 A second, low-affinity LTB4 receptor, BLT2, has also been cloned and characterized.3,4,5 Cayman Chemical’s BLT1 Receptor Monoclonal Antibody is a useful tool for the detection of human BLT1 by flow cytometry, immunofluorescence, and immunohistochemistry. The antibody does not cross react with the other leukotriene receptors (BLT2, CysLT1, or CysLT2) and does not work for Western blot analysis of BLT1.WARNING This product is not for human or veterinary use.
