Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation.1,2,3,4 PGES-1 is a 16 kDa membrane associated protein with glutathione-dependent activity.5,6 The mRNA for PGES-1 is expressed in a variety of tissues including prostate, testes, and small intestine as well as in A549 and HeLa cells. PGES-1 protein expression is increased in A549 cells following treatment with IL-1β.5 Cayman’s PGE Synthase-1 (microsomal) Monoclonal Antibody (Clone 6C6) can be used for Western blot applications. The antibody recognizes PGE Synthase-1 (microsomal) at 16 kDa from human and ovine samples.WARNING This product is not for human or veterinary use.