H2O: soluble10mg/mL, almost clear, greenish-yellow
form
Pale yellow solid.
color
Yellow
optical activity
[α]/D -117±7°, c = 1 in chloroform
Water Solubility
H2O: 10mg/mL, almost clear, greenish-yellow
BRN
5419649
Safety Information
Symbol(GHS)
Signal word
Warning
Hazard statements
H301：Toxic if swalloed
H311：Toxic in contact with skin
H330：Fatal if inhaled
H400：Very toxic to aquatic life
Precautionary statements
P304+P340：IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P320：Specific treatment is urgent (see … on this label).
P330：Rinse mouth.
P405：Store locked up.
Description
1(S),9(R)-(-)-Bicuculline methiodide has been used as a gamma-aminobutyric acid (GABA) antagonist to block inhibition in the semicoronal slices. It has also been used for the preparation of organotypic hippocampal slice cultures (OHSCs).
