BAR 501 impurity;(3R,5S,6S,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-17-[(2R)-5-hydroxypentan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol;(3alpha,5beta,6beta,7alpha)-6-Ethylcholane-3,7,24-triol;Cholane-3,7,24-triol, 6-ethyl-, (3α,5β,6β,7α)-;BAR 501 impurity, 10 mM in DMSO
BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501 impurity (10 μM) induces a 150% increase in luciferase activity in a GP-BAR1 reporter gene assay.1
