BAM15

$32 - $1500

Product nameBAM15
Cas No210302-17-3
MFC16H10F2N6O
MW340.29
EINECS201-118-7
MDL NumberMFCD00373912

Synonyms

BAM15;N,N'-bis(2-fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine;CS-2890;[1,2,5]Oxadiazolo[3,4-b]pyrazine-5,6-diamine, N5,N6-bis(2-fluorophenyl)-;BAM15 >=98% (HPLC);BAM 15 (N5,N6-bis(2-Fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine);inhibit,BAM-15,Inhibitor,BAM 15,BAM15,Mitochondrial Metabolism

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Price

24 prices

Brand less more

Sigma-Aldrich Cayman Chemical Crysdot Tocris TRC AK Scientific ChemScene American Custom Chemicals Corporation Ambeed DC Chemicals
Package less more

50mg 100mg 250mg 500mg 1g 50 1mg 10mg 25mg 5mg 10

Clear All Done

Brand	Packaging	Price	Product name
AK Scientific 5649CC	5mg	$201	5-N,6-N-Bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
Ambeed A924230	5mg	$211	BAM15
Ambeed A924230	10mg	$369	BAM15
Ambeed A924230	25mg	$646	BAM15
American Custom Chemicals Corporation BRS0009220	5MG	$450.09	BAM-15
Cayman Chemical 17811	25mg	$305	BAM15
Cayman Chemical 17811	1mg	$32	BAM15
Cayman Chemical 17811	5mg	$78	BAM15
Cayman Chemical 17811	10mg	$139	BAM15
ChemScene CS-0033152	10mg	$135	BAM15

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Properties

Boiling point	421.7±55.0 °C(Predicted)
Density	1.548±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in DMSO (35 mg/ml)
pka	-2.40±0.50(Predicted)
form	powder
color	white to beige
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS)

Signal word

Danger

Hazard statements

H302：Harmful if swallowed

H361：Suspected of damaging fertility or the unborn child

H372：Causes damage to organs through prolonged or repeated exposure

H410：Very toxic to aquatic life with long lasting effects

Precautionary statements

P201：Obtain special instructions before use.

P264：Wash hands thoroughly after handling.

P264：Wash skin thouroughly after handling.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331：IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P312：Call a POISON CENTER or doctor/physician if you feel unwell.

Description

Typical mitochondrial uncouplers are lipophilic weak acids that increase proton transport into the mitochondrial matrix through an ATP synthase-independent pathway, thereby uncoupling nutrient oxidation from ATP production. These chemicals are used to determine rate of cellular respiration and have antioxidant effects that protect from ischemia-reperfusion injury. Most proton transporter uncouplers, however, exhibit off-target activity that can lead to undesired effects, including plasma membrane depolarization, mitochondrial inhibition, and cytotoxicity. BAM15 is a mitochondrial protonophore uncoupler that does not depolarize the plasma membrane and protects mice from acute renal ischemic-reperfusion injury. In comparison to FCCP , 1-10 μM BAM15 was shown to increase oxygen flux with equal potency as the classic uncoupler, while displaying a higher maximum rate of mitochondrial respiration and less cytotoxicity.

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Suppliers and manufacturers

TargetMol Chemicals Inc.

$59.00/5mg

BAM 15

CAS:210302-17-3
TargetMol Chemicals Inc.

$59.00/5mg

BAM 15

CAS:210302-17-3
Wuhan senwayer century chemical Co.,Ltd

$0.00/1kg

BAM15

CAS:210302-17-3
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Career Henan Chemica Co
Wuhan Topule Biopharmaceutical Co., Ltd
LEAPCHEM CO., LTD.
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific

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