Acid-PEG2-SS-PEG2-acid is a homobifunctional, cleavable PEG linker with carboxylic acid groups at both terminus. Carboxylic acids can be reacted with primary amines in the presences of activators such as EDC and HATU to form stable amide bonds. The disulfide bonds can be cleaved by Dithiothreitol (DTT) reagent.
