N-ACETYL-TRP-GLU-HIS-ASP-7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN TRIFLUOROACETATE SALT
Sigma-Aldrich
A6720
5mg
$534
N-Acetyl-Trp-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin trifluoroacetate salt
Properties
Boiling point
1351.5±65.0°C(Predicted)
Density
1.528±0.06 g/cm3(Predicted)
storage temp.
−20°C
solubility
DMSO/DMF: 20 mM
form
powder
color
yellow
Appearance
White to yellow Solid
Description
Ac-WEHD-AFC is a fluorogenic substrate for group I caspases including caspase-1, -4, and -5. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
