rac-7-hydroxy Propranolol (hydrochloride) is a ring-hydroxylated isomer and metabolite of (±)-propranolol that is an antagonist at β-adrenergic receptors (0.95 potency relative to propranolol).1 It also demonstrates potent vasodilator activity (0.20 potency relative to propranolol; pA2 = 7.58).