2-(2-hydroxy-3-((2-(1h-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)benzonitr ;2-[2-Hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]benzonitrile;3-[2-[3-(o-Cyanophenoxy)-2-hydroxypropylamino]-2-methylpropyl]-1H-indole;Benzonitrile, 2-(2-hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)-;Bucindololum;Bucindololum [inn-latin];Unii-E9uo06K7ce;Bucindolol, 10 mM in DMSO
Bucindolol is a non-selective β-AR adrenoceptor antagonist with additional α1A-AR adrenoceptor blocking activity. Ki values are 1.61, 1.20 and 68.9 nM for β1-AR (β1-), β2-AR(β2-) and α1A-AR (α1-adrenoceptors), respectively. Bucindolol also acts as a weak SR-2A and SR-2B (5-HT2A/2B) antagonist. Bucindolol displays vasodilatory and antihypertensive actions.
![2-[2-Hydroxy-3-[2-(indol-3-yl)-1,1-dimethylethylamino]propoxy]benzonitrile](https://www.chemicalbook.com/CAS/GIF/71119-11-4.gif)