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Description
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(-)-BICUCULLINE METHBROMIDE
(-)-BICUCULLINE METHBROMIDE
$200 - $860
Product name
(-)-BICUCULLINE METHBROMIDE
Cas No
66016-70-4
MF
C21H20NO6.Br
MW
462.294
MDL Number
MFCD00055149
Synonyms
(5S)-5-[(6R)-6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium bromide (1:1);1(S),9(R)-(-)-Bicuculline methbromide;(-)-BICUCULLINE METHBROMIDE;[r-(r*,s*)]-5-(6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquindinium bromide;1(s),9(r)-(-)-bicuculline methobromide;(6R)-6-[(5S)-6,6-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one;d-Bicuculline methobromide;(+)-Bicuculline methobromide|||d-Bicuculline methobromide|||(+)-Bicuculline methobromide
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Biosynth
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25mg
100mg
125mg
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Brand
Packaging
Price
Product name
Biosynth
RCA01670
100mg
$860
1(S),9(R)-(-)-Bicuculline methbromide
Sigma-Aldrich
B7561
25mg
$200
1(S),9(R)-(?)-Bicuculline methbromide
Sigma-Aldrich
B7561
125mg
$798
1(S),9(R)-(?)-Bicuculline methbromide
Properties
storage temp.
2-8°C
solubility
aqueous base: unstable
form
solid
color
white
Water Solubility
Soluble to 50 mM in water
InChIKey
BWXCECYGGMGBHD-GRTNUQQKSA-M
SMILES
[Br-].C[N+]1(C)CCc2cc3OCOc3cc2[C@H]1[C@@H]4OC(=O)c5c6OCOc6ccc45
Safety Information
Symbol(GHS)
Signal word
Danger
Hazard statements
H300:
Fatal if swallowed
H410:
Very toxic to aquatic life with long lasting effects
Precautionary statements
P273:
Avoid release to the environment.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
Description
1(
S
),9(
R
)-(-)-Bicuculline methbromide has been used:
as a γ-aminobutyric acid (GABAA) receptor A antagonist: in cortical neuron culture
in artificial cerebrospinal fluid (ACSF) formature dentate granule neurons
in hypothalamic explant cultures
Suppliers and manufacturers
Aladdin Scientific
Sigma-Aldrich
TargetMol Chemicals Inc.
Nantong QuanYi Biotechnology Co., Ltd
R&D Systems, Inc
Merck KGaA
Biosynth Biological Technology (Suzhou) Co Ltd
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