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3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
$7 - $2493
Product name
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
Cas No
641571-11-1
MF
C11H10F3N3
MW
241.21
EINECS
688-269-6
MDL Number
MFCD11846236
Synonyms
Nilotinib genotoxic impurity 1;3-(4-Methyl-1<i>H</i>-imidazol-1-yl)-5-(trifluoromethyl)aniline;Nilotinib Intemediate 1;1-(3-Amino-5-trifluoromethylphenyl)-4-methylimidazole;3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline;4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl) benzene amine;3-(trifluoromethyl)-5-(4-methyl-1H-imidazol-1-yl)benzenamine;3-(4-Methyl-iMidazol-1-yl)-5-trifluoro-MethylphenylaMine
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A2B
aablocks
Ambeed
Synthonix
Apolloscientific
Chem-Impex
TCI Chemical
AK Scientific
Chemenu
SynQuest Laboratories
AvaChem
Crysdot
TRC
Matrix Scientific
Biosynth
American Custom Chemicals Corporation
Labseeker
Sigma-Aldrich
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5mg
25mg
50mg
100mg
250mg
1.00g
1g
5g
5.00g
10g
25g
50g
100g
250g
500g
2.5kg
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Brand
Packaging
Price
Product name
A2B
AI54285
1g
$7
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
A2B
AI54285
5g
$10
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
A2B
AI54285
10g
$15
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
A2B
AI54285
25g
$19
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
aablocks
AA00IB8X
10g
$17
3-(4-Methyl-1H-Imidazol-1-Yl)-5-(Trifluoromethyl)Aniline
aablocks
AA00IB8X
5g
$14
3-(4-Methyl-1H-Imidazol-1-Yl)-5-(Trifluoromethyl)Aniline
aablocks
AA00IB8X
1g
$8
3-(4-Methyl-1H-Imidazol-1-Yl)-5-(Trifluoromethyl)Aniline
aablocks
AA00IB8X
25g
$21
3-(4-Methyl-1H-Imidazol-1-Yl)-5-(Trifluoromethyl)Aniline
AK Scientific
J11496
100mg
$49
NilotinibImpurity24
Ambeed
A195823
25g
$84
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
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Properties
Melting point
124-126°C
Boiling point
372.14℃[at 101 325 Pa]
Density
1.35
vapor pressure
0Pa at 25℃
storage temp.
Keep in dark place,Inert atmosphere,Room temperature
solubility
DMSO (Slightly), Methanol (Slightly)
form
powder to crystal
color
White to Light gray to Light yellow
Water Solubility
228.6mg/L at 25℃
InChI
InChI=1S/C11H10F3N3/c1-7-5-17(6-16-7)10-3-8(11(12,13)14)2-9(15)4-10/h2-6H,15H2,1H3
InChIKey
WWTGXYAJVXKEKL-UHFFFAOYSA-N
SMILES
C1(N2C=C(C)N=C2)C=C(N)C=C(C(F)(F)F)C=1
LogP
2.42
CAS DataBase Reference
641571-11-1(CAS DataBase Reference)
Safety Information
Symbol(GHS)
Signal word
Danger
Hazard statements
H301:
Toxic if swalloed
H318:
Causes serious eye damage
Precautionary statements
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310:
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338:
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Description
Intermediate in the preparation of Nilotinib.
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$4-2550
Suppliers and manufacturers
Yangzhou Qinyuan Pharmatech Co.,ltd
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
CAS:641571-11-1
Shandong Jihui Chemical Co., Ltd.
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
CAS:641571-11-1
Henan Fengda Chemical Co., Ltd
$1.20
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
CAS:641571-11-1
CONIER CHEM AND PHARMA LIMITED
Capot Chemical Co.,Ltd.
Shanghai Daken Advanced Materials Co.,Ltd
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Shanghai Yingrui Biopharma Co., Ltd.
Anqing Chico Pharmaceutical Co., Ltd.
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