(±)-MDA is a psychedelic and entactogenic drug of the phenethylamine and amphetamine chemical classes. It acts as a serotonergic 5-HT2A receptor agonist and releases monoamines by interacting with monoamine plasmalemmal transporters. R(?)-MDA is more a potent psychoactive agent than its S(+)-enantiomer. Despite being scheduled as a controlled substance in the US since 1970, tablets sold as ‘‘Ecstasy’’ often contain (±)-MDA instead of 3,4-methylenedioxymethamphetamine. This product is intended for research and forensic applications.
