4-OXATETRADECANOIC ACID

4-Oxatetradecanoic acid is an analog of myristate with same chain length but a polar oxygen atom incorporated in place of a methylene group, resulting in reduced hydrophobicity. 4-Oxatetradecanoic acid inhibits HIV replication. Acts as fungicide against Cryptococcus neoformans. 4-Oxatetradecanoic acid may exert its effects by inhibiting the activity of N-myristoyltransferase or by altering the physiology of proteins which have incorporated this analog in place of myristic acid.