1-Stearoyl-2-Arachidonoyl PC-d8

Contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of SAPC by GC- or LC-mass spectrometry. Oxidation of phospholipids in low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that may play a crucial role in cardiovascular and inflammatory diseases. 1-stearoyl-2-arachidonoyl-sn-Glycero-3-phosphocholine (SAPC) is one of the major phospholipid species in LDL. Upon oxidation, SAPC has been shown to induce monocyte-endothelial interactions.